Facile preparation of amine and amino acid adducts of [60]fullerene using chlorofullerene C60Cl6 as a precursor

被引：69
|
作者：
Kornev, Alexey B. [1 ]
Khakina, Ekaterina A. [1 ]
Troyanov, Sergey I. [2 ]
Kushch, Alla A.
Peregudov, Alexander [3 ]
Vasilchenko, Alexey [4 ]
Deryabin, Dmitry G. [4 ]
Martynenko, Vyacheslav M. [1 ]
Troshin, Pavel A. [1 ]
机构：
[1] IPCP RAS, Chernogolovka 141432, Russia
[2] Moscow MV Lomonosov State Univ, Dept Chem, Moscow 119991, Russia
[3] INEOS RAS, Moscow 119991, Russia
[4] OSU, Orenburg 460018, Russia
来源：
CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 44期
关键词：
GENE DELIVERY; C-60; DERIVATIVES; FULLERENES; REDUCTION;
D O I：
10.1039/c2cc00071g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We report a general synthetic approach to the preparation of highly functionalized amine and amino acid derivatives of [60]fullerene starting from readily available chlorofullerene C60Cl6. The synthesized water-soluble amino acid derivative of C-60 demonstrated pronounced antiviral activity, while the cationic amine-based compound showed strong antibacterial action in vitro.
引用
收藏
页码：5461 / 5463
页数：3
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