Facile preparation of amine and amino acid adducts of [60]fullerene using chlorofullerene C60Cl6 as a precursor

被引：69

作者：

Kornev, Alexey B. ^{[1
]}

Khakina, Ekaterina A. ^{[1
]}

Troyanov, Sergey I. ^{[2
]}

Kushch, Alla A.

Peregudov, Alexander ^{[3
]}

Vasilchenko, Alexey ^{[4
]}

Deryabin, Dmitry G. ^{[4
]}

Martynenko, Vyacheslav M. ^{[1
]}

Troshin, Pavel A. ^{[1
]}

机构：

[1] IPCP RAS, Chernogolovka 141432, Russia

[2] Moscow MV Lomonosov State Univ, Dept Chem, Moscow 119991, Russia

[3] INEOS RAS, Moscow 119991, Russia

[4] OSU, Orenburg 460018, Russia

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 44期

关键词：

GENE DELIVERY; C-60; DERIVATIVES; FULLERENES; REDUCTION;

D O I：

10.1039/c2cc00071g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report a general synthetic approach to the preparation of highly functionalized amine and amino acid derivatives of [60]fullerene starting from readily available chlorofullerene C60Cl6. The synthesized water-soluble amino acid derivative of C-60 demonstrated pronounced antiviral activity, while the cationic amine-based compound showed strong antibacterial action in vitro.

引用

页码：5461 / 5463

页数：3

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