Highly diastereoselective sulfonium ylide rearrangements to quaternary substituted indolines

被引：40

作者：

Boyarskikh, Vyacheslav ^{[1
]}

Nyong, Abijah ^{[1
]}

Rainier, Jon D. ^{[1
]}

机构：

[1] Univ Utah, Dept Chem, Salt Lake City, UT 84112 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 29期

关键词：

allylic compounds; indole; rearrangement; sulfur; ylides;

D O I：

10.1002/anie.200801336

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Quat. centers: Sulfonium ylide intermediates generated from halogenated vinyl diazoacetates and 2-thioindoles in the presence of a RhII complex undergo highly diastereoselective [3,3] rearrangements to indolines having an asymmetric quaternary carbon center with an adjacent halogenated stereocenter (see scheme). © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：5374 / 5377

页数：4

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