C-C bond activation with selective functionalization: preparation of unsymmetrical biaryls from benzonitriles

被引：131

作者：

Miller, JA ^{[1
]}

机构：

[1] DSM Catalytica Pharmaceut, Mt View, CA 94043 USA

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 40期

关键词：

D O I：

10.1016/S0040-4039(01)01476-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

For the first time. benzonitriles have been shown to participate in metal-catalyzed cross coupling reactions via activation of the C-CN bond. Thus, reaction of a benzonitrile,vith an aryl Grignard derivative in the presence of a Ni catalyst can readily provide the corresponding unsymmetrical biaryl in high yield and with high selectivity. (C), 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：6991 / 6993

页数：3

共 50 条

[1] Alkynylation of benzonitriles via nickel catalyzed C-C bond activation
Penney, JM
Miller, JA
TETRAHEDRON LETTERS, 2004, 45 (25) : 4989 - 4992
[2] SELECTIVE C-C BOND FORMATION BY THE PHOTOLYSIS OF UNSYMMETRICAL ORGANOMERCURIALS
NUGENT, WA
INORGANICA CHIMICA ACTA-ARTICLES AND LETTERS, 1984, 89 (01): : L17 - L18
[3] Selective Dealkenylative Functionalization of Styrenes via C-C Bond Cleavage
Liu, Jianzhong
Pan, Jun
Luo, Xiao
Qiu, Xu
Zhang, Cheng
Jiao, Ning
RESEARCH, 2020, 2020
[4] Rhodium-catalyzed activation and functionalization of the C-C bond of biphenylene
Iverson, CN
Jones, WD
ORGANOMETALLICS, 2001, 20 (26) : 5745 - 5750
[5] Radical-Promoted C-C Bond Cleavage: A Deconstructive Approach for Selective Functionalization
Morcillo, Sara P.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 58 (40) : 14044 - 14054
[6] C-C BOND ACTIVATION REACTIONS
HOFMANN, P
GERL, T
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1994, 207 : 513 - INOR
[7] C-C Bond Activation Preface
Dong, Guangbin
C-C BOND ACTIVATION, 2014, 346 : V - VI
[8] Catalytic, Directed C-C Bond Functionalization of Styrenes
Onodera, Shunsuke
Togashi, Ryo
Ishikawa, Soya
Kochi, Takuya
Kakiuchi, Fumitoshi
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020, 142 (16) : 7345 - 7349
[9] C-C bond formation via double C-H functionalization: Aerobic oxidative coupling as a method for synthesizing heterocoupled biaryls
Dwight, Timothy A.
Rue, Nicholas R.
Charyk, Dagmara
Josselyn, Ryan
DeBoef, Brenton
ORGANIC LETTERS, 2007, 9 (16) : 3137 - 3139
[10] Transition-Metal-Catalyzed C-C Bond Formation from C-C Activation
Song, Feijie
Wang, Biqin
Shi, Zhang-Jie
ACCOUNTS OF CHEMICAL RESEARCH, 2023, 56 (21) : 2867 - 2886

← 1 2 3 4 5 →