Reconciling Pasteur and Darwin to control infectious diseases

被引：12
作者：
Alizon, Samuel [1 ]
Methot, Pierre-Olivier [2 ]
机构：
[1] UM, UR IRD 224, UMR CNRS 5290, Lab MIVEGEC, Montpellier, France
[2] Univ Laval, Fac Philosophie, Quebec City, PQ, Canada
来源：
PLOS BIOLOGY | 2018年 / 16卷 / 01期
基金：
欧洲研究理事会;
关键词：
EBOLA-VIRUS; ANTIMICROBIAL RESISTANCE; EVOLUTIONARY EMERGENCE; DRUG-RESISTANCE; MEDICINE; VIRULENCE; PATHOGEN; ORIGIN; HOST; ANTIBIOTICS;
D O I：
10.1371/journal.pbio.2003815
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The continual emergence of new pathogens and the increased spread of antibiotic resistance in bacterial populations remind us that microbes are living entities that evolve at rates that impact public health interventions. Following the historical thread of the works of Pasteur and Darwin shows how reconciling clinical microbiology, ecology, and evolution can be instrumental to understanding pathology, developing new therapies, and prolonging the efficiency of existing ones.
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页数：12
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