Serological survey of antibodies to influenza A viruses in a group of people without a history of influenza vaccination

被引：17

作者：

Chen, Y. ^{[1
]}

Zheng, Q. ^{[1
]}

Yang, K. ^{[2
]}

Zeng, F. ^{[1
]}

Lau, S. -Y. ^{[3
]}

Wu, W. L. ^{[3
]}

Huang, S. ^{[1
]}

Zhang, J. ^{[1
]}

Chen, H. ^{[3
]}

Xia, N. ^{[1
]}

机构：

[1] Xiamen Univ, Sch Life Sci, Natl Inst Diagnost & Vaccine Dev Infect Dis, Xiamen, Fujian Province, Peoples R China

[2] Xiamen Int Travel Hlth Care Ctr, Xiamen, Fujian Province, Peoples R China

[3] Univ Hong Kong, Dept Microbiol, State Key Lab Emerging Infect Dis, Pokfulam, Hong Kong, Peoples R China

来源：

CLINICAL MICROBIOLOGY AND INFECTION | 2011年 / 17卷 / 09期

基金：

中国国家自然科学基金; 美国国家卫生研究院;

关键词：

Antibody; H9N2; influenza; pandemic H1N1; prevalence; H1N1; INFLUENZA; INFECTION; CHINA;

D O I：

10.1111/j.1469-0691.2011.03538.x

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

A serological survey for antibodies to influenza viruses was performed in China on a group of people without a history of influenza vaccination. Using the haemagglutination inhibition (HI) assay, we found seropositivity rates for seasonal H3N2 to be significantly higher than those for seasonal H1N1. Samples positive for antibodies to the pandemic (H1N1) 2009 virus increased from 0.6% pre-outbreak to 4.5% (p <0.01) at 1 year post-outbreak. Interestingly, HI and neutralization tests showed that 1.4% of people in the group have antibodies recognizing H9N2 avian influenza viruses, suggesting that infection with this subtype may be more common than previously thought.

引用

页码：1347 / 1349

页数：3

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