Methanol mass poisoning in Iran: role of case finding in outbreak management

被引:76
作者
Hassanian-Moghaddam, Hossein [1 ,2 ]
Nikfarjam, Ali [3 ]
Mirafzal, Amirhossein [4 ]
Saberinia, Amin [4 ]
Nasehi, Abbas Ali [5 ]
Asl, Hossein Masoumi [6 ]
Memaryan, Nadereh [3 ]
机构
[1] Loghman Hakim Hosp, Toxicol Res Ctr, Tehran 13336, Iran
[2] Shahid Beheshti Univ Med Sci, Fac Med, Dept Clin Toxicol, Tehran, Iran
[3] Minist Hlth, Mental & Social Hlth & Subst Abuse Off, Tehran, Iran
[4] Kerman Univ Med Sci, Dept Emergency Med, Kerman, Iran
[5] Iran Helal Inst Appl Sci & Technol, Tehran, Iran
[6] Iran Univ Med Sci, Dept Pediat Infect Dis, Tehran, Iran
关键词
methanol; poisoning; outbreak; epidemics; mortality; intoxication; CLINICAL-FEATURES; EPIDEMIOLOGY;
D O I
10.1093/pubmed/fdu038
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
There are no guidelines addressing the public health aspects of methanol poisoning during larger outbreaks. The current study was done to discuss the role of active case finding and a national guideline that organizes all available resources according to a triage strategy in the successful management of a methanol mass poisoning in Rafsanjan, Iran, in May 2013. A retrospective cross-sectional study was performed reviewing the outbreak Emergency Operation Center files. The objectives were to describe the characteristics, management and outcome of a methanol outbreak using Active Case Finding to trace the victims. A total of 694 patients presented to emergency departments in Rafsanjan after public announcement of the outbreak between 29th May and 3rd June 2013. The announcement was mainly performed via short message service (SMS) and local radio broadcasting. A total of 361 cases were observed and managed in Rafsanjan and 333 were transferred to other cities. Seventy-five and 100 patients underwent hemodialysis (HD), retrospectively. The main indication for HD was refractory metabolic acidosis. Eight patients expired due to the intoxication. Except for the deceased cases, no serum methanol level was available. In developing countries, where diagnostic resources are limited, use of active case finding and developing national guidelines can help in the management of large outbreaks of methanol poisonings.
引用
收藏
页码:354 / 359
页数:6
相关论文
共 21 条
[11]   Anion and osmolal gaps in the diagnosis of methanol poisoning: clinical study in 28 patients [J].
Hovda, KE ;
Hunderi, OH ;
Rudberg, N ;
Froyshov, S ;
Jacobsen, D .
INTENSIVE CARE MEDICINE, 2004, 30 (09) :1842-1846
[12]  
Hovda KE, 2011, 10 SCI C AS PAC ASS
[13]   Methanol contamination of Romanian home-distilled alcohol [J].
Levy, P ;
Hexdall, A ;
Gordon, P ;
Boeriu, C ;
Heller, M ;
Nelson, L .
JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY, 2003, 41 (01) :23-28
[14]   Methanol poisoning in Iran, from 2000 to 2009 [J].
Massoumi, Gholamreza ;
Saberi, Kianoosh ;
Eizadi-Mood, Nastaran ;
Shamsi, Mohammad ;
Alavi, Mostafa ;
Morteza, Afsaneh .
DRUG AND CHEMICAL TOXICOLOGY, 2012, 35 (03) :330-333
[15]  
Moghadami M, 2008, IRAN J MED SCI, V33, P22
[16]   Methanol mass poisoning in Estonia: Outbreak in 154 patients [J].
Paasma, R. ;
Hovda, K. E. ;
Tikkerberi, A. ;
Jacobsen, D. .
CLINICAL TOXICOLOGY, 2007, 45 (02) :152-157
[17]   Risk factors related to poor outcome after methanol poisoning and the relation between outcome and antidotes - a multicenter study [J].
Paasma, Raido ;
Hovda, Knut Erik ;
Hassanian-Moghaddam, Hossein ;
Brahmi, Nozha ;
Afshari, Reza ;
Sandvik, Leiv ;
Jacobsen, Dag .
CLINICAL TOXICOLOGY, 2012, 50 (09) :823-831
[18]  
Pelclova D, 2013, CLIN TOXICOL, V51, P252
[19]   Using Poison Center Data for National Public Health Surveillance for Chemical and Poison Exposure and Associated Illness [J].
Wolkin, Amy F. ;
Martin, Colleen A. ;
Law, Royal K. ;
Schier, Josh G. ;
Bronstein, Alvin C. .
ANNALS OF EMERGENCY MEDICINE, 2012, 59 (01) :56-61
[20]  
Zachariah R, 2003, INT J TUBERC LUNG D, V7, P1033