Machine learning to empower electrohydrodynamic processing

被引:20
作者
Wang, Fanjin [1 ]
Elbadawi, Moe [1 ]
Tsilova, Scheilly Liu [1 ]
Gaisford, Simon [1 ]
Basit, Abdul W. [1 ]
Parhizkar, Maryam [1 ]
机构
[1] UCL, UCL Sch Pharm, Dept Pharmaceut, 29-39 Brunswick Sq, London WC1N 1AX, England
来源
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS | 2022年 / 132卷
基金
英国工程与自然科学研究理事会;
关键词
3D printing drug products; Continuous manufacturing; Nanotechnology; Digital healthcare technology; Informatics; Functional materials; 2D materials; ARTIFICIAL NEURAL-NETWORKS; STRUCTURE-PROPERTY RELATIONSHIP; SUPPORT VECTOR MACHINE; GAUSSIAN MIXTURE MODEL; DIMENSIONALITY REDUCTION; FEATURE-SELECTION; DRUG DISCOVERY; NANOFIBERS; PREDICTION; SYSTEM;
D O I
10.1016/j.msec.2021.112553
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
Electrohydrodynamic (EHD) processes are promising healthcare fabrication technologies, as evidenced by the number of commercialised and food-and-drug administration (FDA)-approved products produced by these processes. Their ability to produce both rapidly and precisely nano-sized products provides them with a unique set of qualities that cannot be matched by other fabrication technologies. Consequently, this has stimulated the development of EHD processing to tackle other healthcare challenges. However, as with most technologies, time and resources will be needed to realise fully the potential EHD processes can offer. To address this bottleneck, researchers are adopting machine learning (ML), a subset of artificial intelligence, into their workflow. ML has already made ground-breaking advancements in the healthcare sector, and it is anticipated to do the same in the materials domain. Presently, the application of ML in fabrication technologies lags behind other sectors. To that end, this review showcases the progress made by ML for EHD workflows, demonstrating how the latter can benefit greatly from the former. In addition, we provide an introduction to the ML pipeline, to help encourage the use of ML for other EHD researchers. As discussed, the merger of ML with EHD has the potential to expedite novel discoveries and to automate the EHD workflow.
引用
收藏
页数:14
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