What is the role of inflammatory markers in predicting spontaneous ureteral stone passage?

被引:6
作者
Senel, Cagdas [1 ]
Aykanat, Ibrahim Can [2 ]
Asfuroglu, Ahmet [3 ]
Keten, Tanju [3 ]
Balci, Melih [3 ]
Aslan, Yilmaz [3 ]
Tuncel, Altug [4 ]
机构
[1] Balikesir Univ, Urol, TR-53003 Balikesir, Turkey
[2] Yozgat State Hosp, Urol, TR-233009 Yozgat, Turkey
[3] Etimesgut State Hosp, Urol, Ankara, Turkey
[4] Univ Hlth Sci, Ankara State Hosp, Sch Med, Urol, TR-448249 Ankara, Turkey
关键词
ureteral stone; inflammatory markers; spontaneous stone passage; prognosis; TO-LYMPHOCYTE RATIO; MANAGEMENT; LOCATION; CALCULI; SIZE;
D O I
10.1055/a-1703-3099
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Purpose: To investigate the role of inflammatory markers in predicting the spontaneous passage of ureteral stones. Methods: We retrospectively reviewed 279 patients with ureteral stones sized 4-10 mm that were managed conservatively. The patients were divided into two groups: Group 1 consisted of 137 patients who passed the stone spontaneously; Group 2 comprised 142 patients without spontaneous stone passage. The groups were compared using the Mann-Whitney U and chi-square tests. In addition, univariate and multivariate analyses were performed to identify the significance of the parameters. Results: The mean age of the patients was 41.2 years. The patients in Group 1 had a significantly lower mean stone size, white blood cell count and neutrophil count. In addition, stone location, presence of hydronephrosis and history of urolithiasis were significantly different between the groups. Neutrophil percentage, neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio were insignificantly lower in Group 1. In a multivariate analysis, stone size, distal location and hydronephrosis status significantly predicted the spontaneous stone passage. However, inflammatory markers including white blood cell count, neutrophil count and neutrophil-to-lymphocyte ratio could not determine the likelihood of spontaneous stone passage. Conclusion: Our results suggest that inflammatory markers are no meaningful parameters for the prediction of spontaneous stone passage.
引用
收藏
页码:448 / 453
页数:6
相关论文
共 28 条
[1]   Inflammatory serum markers predicting spontaneous ureteral stone passage [J].
Abou Heidar, Nassib ;
Labban, Muhieddine ;
Bustros, Gerges ;
Nasr, Rami .
CLINICAL AND EXPERIMENTAL NEPHROLOGY, 2020, 24 (03) :277-283
[2]   Association between grades of Hydronephrosis & detection of urinary stones by ultrasound imaging [J].
Alshoabi, Sultan Abdulwadoud .
PAKISTAN JOURNAL OF MEDICAL SCIENCES, 2018, 34 (04) :955-958
[3]  
Assimos D, 2016, J UROLOGY, V196, P1161, DOI 10.1016/j.juro.2016.05.091
[4]   Analysis of factors affecting spontaneous expulsion of ureteral stones that may predict unfavorable outcomes during watchful waiting periods: What is the influence of diabetes mellitus on the ureter? [J].
Choi, Taesoo ;
Yoo, Koo Han ;
Choi, Seung-Kwon ;
Kim, Dong Soo ;
Lee, Dong-Gi ;
Min, Gyeong Eun ;
Jeon, Seung Hyun ;
Lee, Hyung-Lae ;
Jeong, In-Kyung .
KOREAN JOURNAL OF UROLOGY, 2015, 56 (06) :455-460
[5]   Can serum procalcitonin levels be useful in predicting spontaneous ureteral stone passage? [J].
Cilesiz, Nusret Can ;
Ozkan, Arif ;
Kalkanli, Arif ;
Eroglu, Ali ;
Gezmis, Cem Tugrul ;
Simsek, Berkan ;
Arslan, Burak .
BMC UROLOGY, 2020, 20 (01)
[6]   Relationship of spontaneous passage of ureteral calculi to stone size and location as revealed by unenhanced helical CT [J].
Coll, DM ;
Varanelli, MJ ;
Smith, RC .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2002, 178 (01) :101-103
[7]   Cost-effectiveness comparison of ureteral calculi treated with ureteroscopic laser lithotripsy versus shockwave lithotripsy [J].
Cone, Eugene B. ;
Pareek, Gyan ;
Ursiny, Michal ;
Eisner, Brian .
WORLD JOURNAL OF UROLOGY, 2017, 35 (01) :161-166
[8]   What is the normal value of the neutrophil-to-lymphocyte ratio? [J].
Forget P. ;
Khalifa C. ;
Defour J.-P. ;
Latinne D. ;
Van Pel M.-C. ;
De Kock M. .
BMC Research Notes, 10 (1) :1-4
[9]   The Platelet-to-Lymphocyte Ratio as an Inflammatory Marker in Rheumatic Diseases [J].
Gasparyan, Armen Yuri ;
Ayvazyan, Lilit ;
Mukanova, Ulzhan ;
Yessirkepov, Marlen ;
Kitas, George D. .
ANNALS OF LABORATORY MEDICINE, 2019, 39 (04) :345-357
[10]   Which Patients Should Have Early Surgical Intervention for Acute Ureteral Colic? [J].
Innes, Grant D. ;
Scheuermeyer, Frank X. ;
McRae, Andrew D. ;
Law, Michael R. ;
Teichman, Joel M. H. ;
Grafstein, Eric ;
Andruchow, James E. .
JOURNAL OF UROLOGY, 2021, 205 (01) :152-158