Mutation scan screening of Echinococcus granulosus isolates of Indian origin

被引：6

作者：

Bhattacharya, D. ^{[1
]}

Pan, D. ^{[1
]}

Bera, A. K. ^{[1
]}

Konar, A. ^{[1
]}

Das, S. K. ^{[1
]}

机构：

[1] Indian Vet Res Inst, Eastern Reg Stn, Kolkata 70037, W Bengal, India

来源：

VETERINARY RESEARCH COMMUNICATIONS | 2008年 / 32卷 / 06期

关键词：

goat; sheep; Echinococcus granulosus; India;

D O I：

10.1007/s11259-008-9039-9

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

During the present investigation a total of forty Indian animal isolates were screened by single strand conformation polymorphism (SSCP) collected from sheep, goat, cattle and buffalo. The result of the study indicated that nuclear variants of Echinococcus granulosus were present in both small and large ruminants. SSCP phenotypes of AgB, intron of actin II and Hbx-2 have been deduced. Presence of nuclear variants due to mutation of E. granulosus has been discussed depending on hypotheses imparted earlier in literature. High polymophism of AgB demands further investigation because the gene is related with immune evasion and infectivity. This communication reports for the first time the comparative profile of Indian goat, sheep, cattle and buffalo isolates of E. granulosus complex.

引用

页码：427 / 432

页数：6

共 19 条

[1]

[Anonymous], 2001, Anal Biochem

[2]

Bhattacharya D., 2000, Journal of Parasitology and Applied Animal Biology, V9, P25

[3] Genotypic characterisation of Indian cattle, buffalo and sheep isolates of Echinococcus granulosus [J].

Bhattacharya, D. ;

Bera, A. K. ;

Bera, B. C. ;

Maity, A. ;

Das, S. K. .

VETERINARY PARASITOLOGY, 2007, 143 (3-4) :371-374

[4] Molecular characterisation of a novel 8-kDa subunit of Echinococcus granulosus antigen B [J].

Fernandez, V ;

Ferreira, HB ;

Fernandez, C ;

Zaha, A ;

Nieto, A .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1996, 77 (02) :247-250

[5] SEQUENCE HETEROGENEITY OF THE ECHINOCOCCAL ANTIGEN-B [J].

FROSCH, P ;

HARTMANN, M ;

MUHLSCHLEGEL, F ;

FROSCH, M .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1994, 64 (01) :171-175

[6] ON BIOLOGY AND MORPHOLOGY OF ECHINOCOCCUS GRANULOSUS (BATSCH 1786) OF BUFFALO-DOG ORIGIN [J].

GILL, HS ;

RAO, BV .

PARASITOLOGY, 1967, 57 :695-+

[7] Breeding systems in Echinococcus granulosus (Cestoda; Taeniidae):: selfing or outcrossing [J].

Haag, KL ;

Araújo, AM ;

Gottstein, B ;

Siles-Lucas, M ;

Thompson, RCA ;

Zaha, A .

PARASITOLOGY, 1999, 118 :63-71

[8] Contingent, non-neutral evolution in a multicellular parasite:: natural selection and gene conversion in the Echinococcus granulosus antigen B gene family [J].

Haag, KL ;

Alves-Junior, L ;

Zaha, A ;

Ayala, FJ .

GENE, 2004, 333 :157-167

[9] ROSTELLAR HOOK MORPHOLOGY OF ECHINOCOCCUS-GRANULOSUS (BATSCH, 1786) FROM NATURAL AND EXPERIMENTAL AUSTRALIAN HOSTS, AND ITS IMPLICATIONS FOR STRAIN RECOGNITION [J].

HOBBS, RP ;

LYMBERY, AJ ;

THOMPSON, RCA .

PARASITOLOGY, 1990, 101 :273-281

[10]

Lymbery AJ, 1997, EVOLUTION, V51, P289, DOI [10.1111/j.1558-5646.1997.tb02411.x, 10.2307/2410983]

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