Initial post marketing experience with lacosamide in adult patients with epilepsy

被引:19
作者
Harden, Cynthia L. [1 ]
Cohn, Aaron [2 ]
Lowe, Merredith [2 ]
Serrano, Enrique [2 ]
机构
[1] N Shore Long Isl Jewish Hlth Syst, Hofstra N Shore LIJ Sch Med, Cushing Neurosci Inst, New Hyde Pk, NY 11040 USA
[2] Univ Miami, Miller Sch Med, Dept Neurol, Div Epilepsy, Miami, FL 33136 USA
关键词
Epilepsy; Lacosamide; Responder rate; Dose; Correlation; Adverse effects;
D O I
10.1016/j.eplepsyres.2011.09.010
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The outcomes of adult epilepsy patients prescribed lacosamide for additional seizure control. Responders were defined as having at least a 50% decrease in seizure frequency Sixty-seven patients were evaluated. Forty-six out of 67 patients (69%) were responders. Twelve of 14 patients not taking sodium channel-acting AEDs were responders (86%) and 34/53 patients taking sodium channel-acting AEDs were responders (64%) (difference not significant). (C) 2011 Elsevier B.V. All rights reserved.
引用
收藏
页码:260 / 263
页数:4
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