Severe infections due to Francisella tularensis ssp. holarctica in solid organ transplant recipient: report of two cases and review of literature

被引:10
作者
Bahuaud, Olivier [1 ,2 ]
Le Brun, Cecile [3 ]
Chalopin, Thomas [1 ,2 ]
Lacasse, Marion [1 ,2 ]
Le Marec, Julien [1 ,2 ]
Pantaleon, Clemence [4 ]
Nicolas, Charlotte [5 ]
Barbier, Louise [2 ,6 ]
Bernard, Louis [1 ,2 ]
Lemaignen, Adrien [1 ,2 ]
机构
[1] Hosp Bretonneau, Univ Hosp Tours, Dept Internal Med & Infect Dis, 2 Blvd Tonnelle, F-37044 Tours 9, France
[2] Francois Rabelais Univ, Tours, France
[3] Univ Hosp Tours, Dept Bacteriol, Tours, France
[4] Univ Hosp Tours, Dept Cardiol, Tours, France
[5] Univ Hosp Tours, Dept Hepatol, Tours, France
[6] Univ Hosp Tours, Dept Digest Surg Hepatobiliary Surg & Liver Trans, Tours, France
关键词
Francisella tularensis; Solid organ transplant; Pneumonia; Molecular diagnosis; Prevention; BIOVAR PALAEARCTICA; TULAREMIA;
D O I
10.1186/s12879-019-3863-0
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
BackgroundTularemia is a rare zoonotic infection caused by bacterium Francisella tularensis. It has been well described in immunocompetent patients but poorly described in immunocompromised patients notably in solid organ transplant recipients.Case presentationsWe report here two cases of tularemia in solid organ transplant recipients including first case after heart transplant. We also carried out an exhaustive review of literature describing characteristics of this infection in solid organ transplant recipients.
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页数:6
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