Positron emission tomography as predictor of rectal cancer response during or following neoadjuvant chemoradiation

被引:6
作者
Hopkins, Shane [1 ]
Fakih, Marwan [2 ]
Yang, Gary Y. [1 ]
机构
[1] Roswell Pk Canc Inst, Dept Radiat Med, Elm & Carlton Str, Buffalo, NY 14263 USA
[2] Roswell Pk Canc Inst, Dept Med, Buffalo, NY 14263 USA
关键词
Positron emission tomography; Rectal cancer; Neoadjuvant therapy; PREOPERATIVE CHEMORADIATION; F-18-FDG PET; FDG-PET; THERAPY; RADIOCHEMOTHERAPY; RADIATION; CHEMOTHERAPY; RADIOTHERAPY; CT;
D O I
10.4251/wjgo.v2.i5.213
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Positron emission tomography (PET) shows great promise as a tool to evaluate the effectiveness of rectal cancer neoadjuvant therapy as it has demonstrated high predictive value in several studies. Creating a standardized method of using PET has the potential to reduce ineffective treatments. However, relevant studies have been heterogenous in approach, making any unified standard difficult to establish. PET related parameters used to assess treatment response include magnitude and change of standard uptake value, total lesion glycolysis, and visual response. Finding the best evaluation interval and parameters to use for interpreting PET results in the neoadjuvant treatment of rectal cancer needs additional study. (C) 2010 Baishideng. All rights reserved.
引用
收藏
页码:213 / 217
页数:5
相关论文
共 28 条
[11]  
Janssen MH, 2009, INT J RAD ONCOL BIOL
[12]  
Jemal A, 2009, CA-CANCER J CLIN, V59, P225, DOI [10.3322/caac.20006, 10.3322/caac.21387]
[13]  
Kalff V, 2006, J NUCL MED, V47, P14
[14]   Can molecular imaging predict response to preoperative chemoradiation in patients with rectal cancer? A Fox Chase Cancer Center prospective experience [J].
Konski, A ;
Hoffman, J ;
Sigurdson, E ;
Haluszka, O ;
Engstrom, P ;
Cheng, JD ;
Cohen, SJ ;
Watson, JC ;
Eisenberg, D ;
McGarrity, E ;
Freedman, G ;
Meropol, NJ .
SEMINARS IN ONCOLOGY, 2005, 32 (06) :S63-S67
[15]   USE OF MOLECULAR IMAGING TO PREDICT CLINICAL OUTCOME IN PATIENTS WITH RECTAL CANCER AFTER PREOPERATIVE CHEMOTHERAPY AND RADIATION [J].
Konski, Andre ;
Li, Tianyu ;
Sigurdson, Elin ;
Cohen, Steven J. ;
Small, William, Jr. ;
Spies, Stewart ;
Yu, Jian Q. ;
Wahl, Andrew ;
Stryker, Steven ;
Meropol, Neal J. .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2009, 74 (01) :55-59
[16]   PET/CT and histopathologic response to preoperative chemoradiation therapy in locally advanced rectal cancer [J].
Kristiansen, Charlotte ;
Loft, Annika ;
Berthelsen, Anne K. ;
Graff, Jesper ;
Lindebjerg, Jan ;
Bisgaard, Claus ;
Jakobsen, Anders .
DISEASES OF THE COLON & RECTUM, 2008, 51 (01) :21-25
[18]   Preoperative radiation response evaluated by 18-fluorodeoxyglucose positron emission tomography predicts survival in locally advanced rectal cancer [J].
Nakagawa, Keiichi ;
Yamashita, Hideomi ;
Nakamura, Naoki ;
Igaki, Hiroshi ;
Tago, Masao ;
Hosoi, Yoshio ;
Momose, Toshimitsu ;
Ohtomo, Kuni ;
Muto, Tetsuichiro ;
Nagawa, Hirokazu .
DISEASES OF THE COLON & RECTUM, 2008, 51 (07) :1055-1060
[19]   FDG-PET after radiotherapy is a good prognostic indicator of rectal cancer [J].
Oku, S ;
Nakagawa, K ;
Momose, T ;
Kumakura, Y ;
Abe, A ;
Watanabe, T ;
Ohtomo, K .
ANNALS OF NUCLEAR MEDICINE, 2002, 16 (06) :409-416
[20]  
Pan TS, 2005, J NUCL MED, V46, P1481