Biotransformation of paclitaxel by cell suspension cultures of Eucalyptus perriniana

被引：10

作者：

Hamada, H

Sanada, K

Furuya, T

Kawabe, S

Jaziri, M

机构：

[1] OKAYAMA UNIV SCI,DEPT APPL SCI,OKAYAMA 700,JAPAN

[2] KURASHIKI UNIV SCI & ARTS,DEPT LIBERAL ARTS & SCI,KURASHIKI,OKAYAMA 712,JAPAN

[3] FREE UNIV BRUSSELS,LAB PLANT MORPHOL,B-1160 BRUSSELS,BELGIUM

来源：

NATURAL PRODUCT LETTERS | 1996年 / 9卷 / 01期

关键词：

paclitaxel; taxoids; Eucalyptus; cell suspension culture; biotransformation;

D O I：

10.1080/10575639608043577

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Incubation of Eucalyptus perriniana cells in medium containing paclitaxel lead to the isolation of three taxoid derivatives which were identified by H-1 NMR and MS spectrometry data as baccatin III, 10-deacetylbaccatin III and 2-debenzoyltaxol. No transformation occurs in medium without Eucalyptus cells.

引用

收藏

页码：47 / 52

页数：6

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