Effects of pulmonary afterload on the hemodynamics after the hemi-Fontan procedure

被引:19
作者
Guadagni, G
Bove, EL
Migliavacca, F
Dubini, G
机构
[1] Politecn Milan, Dept Energy Engn, I-20133 Milan, Italy
[2] Politecn Milan, Dept Bioengn, I-20133 Milan, Italy
[3] Univ Michigan, Ann Arbor, MI 48109 USA
[4] Politecn Milan, Lab Biol Struct Mech, I-20133 Milan, Italy
关键词
hemi-Fontan procedure; hemodynamics; pulmonary perfusion;
D O I
10.1016/S1350-4533(01)00035-2
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
A computational fluid dynamics study based on the application of the finite volume method has been performed to investigate the effects of the pulmonary afterload on the hemodynamics after the hemi-Fontan procedure. This operation is generally used as part of a series of staged procedures to treat complex congenital malformations of the heart. It consists of re-directing the superior vena caval flow from the right atrium into the pulmonary arteries, by-passing the right ventricle while excluding the inferior caval flow from the lungs. To reproduce correctly the pulmonary afterload conditions, a simplified lumped-parameter mechanical model of the pulmonary circulation has been developed and linked to the finite volume solver. In addition, the effect of a stenosis in the left pulmonary artery was also examined. In this paper the adopted methodology is presented, together with some of the preliminary results. The model has been used to simulate the local fluid dynamics for different values of the pulmonary arteriolar resistance and lung resistances, allowing a quantitative evaluation of the dissipated energy and the flow distribution into the lungs. The results show that both flow distribution into the lungs and energy dissipation after the hemi-Fontan procedure are only minimally affected by the pulmonary arteriolar resistance. (C) 2001 IPEM. Published by Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:293 / 298
页数:6
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