Effect of kojic acid on the hydroxylation of L-tyrosine and tyramine by mushroom tyrosinase

被引:3
|
作者
Kahn, V [1 ]
Ben Shalom, N [1 ]
Zakin, V [1 ]
机构
[1] Agr Res Org, Volcani Ctr, Dept Food Sci, IL-50250 Bet Dagan, Israel
关键词
D O I
10.1111/j.1745-4514.1998.tb00256.x
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Kojic acid inhibits effectively the rate of L-tyrosine and tyramine hydroxylation by mushroom tyrosinase. It also affects the spectrum of product(s) formed, this being due to the ability of dopaquinone and dopamine-(o) under bar-quinone to oxidize kojic acid to a yellow product(s). Kojic acid prevents the conversion of these (o) under bar-quinones to their corresponding melanins. An insoluble yellow product(s) is formed when tyramine, but not L-tyrosine, is incubated with tyrosinase for 20 h in the presence of excess kojic acid.
引用
收藏
页码:455 / 474
页数:20
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