Multifunctional Nanoparticles for Dual Imaging

被引:100
作者
Ali, Z. [1 ,2 ]
Abbasi, A. Z. [1 ,2 ]
Zhang, F. [1 ,2 ]
Arosio, P. [4 ,5 ]
Lascialfari, A. [4 ,5 ,6 ,7 ]
Casula, M. F. [8 ,9 ]
Wenk, A. [10 ]
Kreyling, W. [10 ]
Plapper, R. [11 ]
Seidel, M. [11 ]
Niessner, R. [11 ]
Knoell, J. [3 ]
Seubert, A. [3 ]
Parak, W. J. [1 ,2 ]
机构
[1] Univ Marburg, Fachbereich Phys, D-3550 Marburg, Germany
[2] Univ Marburg, Wissensch Zentrum Mat Wissensch, D-3550 Marburg, Germany
[3] Univ Marburg, Fachbereich Chem, D-3550 Marburg, Germany
[4] Univ Milan, Dipartimento Sci Mol Applicate Biosistemi, Milan, Italy
[5] CNR Ist Nanosci, Modena, Italy
[6] Univ Pavia, Dipartimento Fis A Volta, I-27100 Pavia, Italy
[7] Univ Pavia, INSTM, I-27100 Pavia, Italy
[8] Univ Cagliari, Dipartimento Sci Chim, Monserrato, Italy
[9] Univ Cagliari, INSTM, Monserrato, Italy
[10] Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Lung Biol & Dis, Comprehens Pneumol Ctr, Neuherberg, Germany
[11] Tech Univ Munich, Inst Hydrochem, Munich, Germany
关键词
POSITRON-EMISSION-TOMOGRAPHY; IN-VIVO; QUANTUM DOTS; MAGNETIC NANOPARTICLES; AMPHIPHILIC POLYMER; INORGANIC NANOPARTICLES; COLLOIDAL NANOPARTICLES; FLUORESCENCE; NANOCRYSTALS; VITRO;
D O I
10.1021/ac103261y
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
For imaging with different modalities, labels, which provide contrast for all modalities, are required. Colloidal nanoparticles composed out of an inorganic core and a polymer shell offer progress in this direction. Both, the core and the polymer shell, can be synthesized to be fluorescent, magnetic, or radioactive. When different cores are combined with different polymer shells, different types of particles for dual imaging can be obtained, as for example, fluorescent cores with radioactive polymer shells. Properties and perspectives of such nanoparticles for multimodal imaging are discussed.
引用
收藏
页码:2877 / 2882
页数:6
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