Hair follicles - An efficient storage and penetration pathway for topically applied substances

被引：132

作者：

Lademann, J. ^{[1
]}

Knorr, F.

Richter, H.

Blume-Peytavi, U. ^{[2
]}

Vogt, A. ^{[2
]}

Antoniou, C. ^{[3
]}

Sterry, W.

Patzelt, A.

机构：

[1] Charite Univ Med Berlin, Dept Dermatol, Ctr Expt & Appl Cutaneous Physiol, DE-10117 Berlin, Germany

[2] Charite Univ Med Berlin, Clin Res Ctr Hair & Skin Sci, Dept Dermatol & Allergol, DE-10117 Berlin, Germany

[3] Univ Athens, Hosp A Syggros, Dept Dermatol & Photobiol, Athens, Greece

来源：

SKIN PHARMACOLOGY AND PHYSIOLOGY | 2008年 / 21卷 / 03期

关键词：

hair follicles; follicular penetration; nanoparticles; skin barrier; follicle reservoir; stratum corneum;

D O I：

10.1159/000131079

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

In the past, it was assumed that the intercellular route was the only relevant penetration pathway for topically applied substances. Recent results on follicular penetration obtained at the Center for Experimental and Applied Cutaneous Physiology, Charite - Universitatsmedizin Berlin, Germany, emphasize that the hair follicles represent a highly relevant and efficient penetration pathway and reservoir for topically applied substances. Copyright (C) 2008 S. Karger AG, Basel.

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页码：150 / 155

页数：6

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