Transcatheter Valve-in-Valve Implantation Using Core Valve Revalving System for Failed Surgical Aortic Bioprostheses

被引：59

作者：

Bedogni, Francesco ^{[1
]}

Laudisa, Maria Luisa ^{[1
]}

Pizzocri, Samuele ^{[1
]}

Tamburino, Corrado ^{[2
]}

Ussia, Gian Paolo ^{[2
]}

Petronio, Anna Sonia ^{[3
]}

Napodano, Massimo ^{[4
]}

Ramondo, Angelo ^{[5
]}

Presbitero, Patrizia ^{[6
]}

Ettori, Federica ^{[7
]}

Santoro, Gennaro ^{[8
]}

Klugman, Silvio ^{[9
]}

De Marco, Federico ^{[9
]}

Brambilla, Nedy ^{[1
]}

Testa, Luca ^{[1
]}

机构：

[1] Ist Clin S Ambrogio, Dept Intervent Cardiol, I-20149 Milan, Italy

[2] Ferrarotto Hosp, Catania, Italy

[3] Univ Pisa, Cardiothorac & Vasc Dept, Azienda Osped, Pisa, Italy

[4] Univ Padua, Dept Cardiac Thorac & Vasc Sci, Padua, Italy

[5] Osped Bassano Grappa, Vicenza, Italy

[6] Ist Clin Humanitas, Milan, Italy

[7] Spedali Civil Brescia, Cardiothorac Dept, I-25125 Brescia, Italy

[8] Careggi Hosp, Florence, Italy

[9] Osped Niguarda Ca Granda, Milan, Italy

来源：

JACC-CARDIOVASCULAR INTERVENTIONS | 2011年 / 4卷 / 11期

关键词：

CoreValve Revalving System; failed surgical aortic bioprosthesis; TAVI; FOLLOW-UP; COREVALVE;

D O I：

10.1016/j.jcin.2011.10.002

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objectives The purpose of this study was to evaluate the performance of Core Valve Revalving System (CRS) (Medtronic, Minneapolis, Minnesota) implantation in patients with failed aortic bioprostheses. Background Transcatheter aortic valve implantation with the CRS is an effective option in high-risk patients with severe aortic stenosis. It may be an option for patients with a failed aortic bioprosthesis, especially when the risk of a surgical redo is deemed prohibitive. Methods CRS "valve-in-valve" implantation was performed in 25 high-risk patients with a failed bioprosthesis. Their mean age was 82.4 +/- 3.2 years. New York Heart Association functional classes III and IV were present in 21 and 4 patients, respectively. The logistic EuroSCORE was 31.5 +/- 14.8%, whereas the Society of Thoracic Surgeons score was 8.2 +/- 4.2. Patients/prostheses were divided in type A (mainly stenotic, n = 9) and type B (mainly regurgitant, n = 16). Results The implantation success rate was 100%. In group A, the peak aortic gradient significantly decreased from 77.6 +/- 21.6 mm Hg to 34.6 +/- 19.4 mm Hg (p = 0.001). In all but 2 patients in group B, no significant regurgitation was observed post-implantation. No patients died during the procedure. At 30 days, there were 3 deaths (12%), 2 myocardial infarctions (8%), and 3 atrioventricular blocks requiring pacemaker implantation (12%). At a mean follow-up of 6 months, there were another death (survival rate of 84%) and a pacemaker implantation (cumulative incidence of 16%). New York Heart Association functional class improved in all patients to I and II. Conclusions CRS implantation was feasible and effective regardless of the prevalent mode of failure. This finding may significantly affect the treatment of patients with a failed bioprosthesis deemed at a prohibitive risk for surgical redo. (J Am Coll Cardiol Inty 2011;4:1228-34) (C) 2011 by the American College of Cardiology Foundation

引用

页码：1228 / 1234

页数：7

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