Epidemiological and clinical boundaries of heart failure with preserved ejection fraction

被引：24

作者：

Gentile, Francesco ^{[1
,2
]}

Ghionzoli, Nicolo ^{[3
]}

Borrelli, Chiara ^{[1
,4
]}

Vergaro, Giuseppe ^{[1
,4
]}

Pastore, Maria Concetta ^{[3
]}

Cameli, Matteo ^{[3
]}

Emdin, Michele ^{[1
,4
]}

Passino, Claudio ^{[1
,4
]}

Giannoni, Alberto ^{[1
,4
]}

机构：

[1] Fdn Toscana G Monasterio, Dept Cardiol & Cardiovasc Med, I-56124 Pisa, Italy

[2] Univ Hosp Pisa, Div Cardiol, Cardiothorac Dept, I-56124 Pisa, Italy

[3] Univ Siena, Div Cardiol, Dept Med Biotechnol, I-53100 Siena, Italy

[4] Scuola Super Sant Anna, Inst Life Sci, Piazza Martiri Liberta 33, I-56127 Pisa, Italy

来源：

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY | 2022年 / 29卷 / 08期

关键词：

Heart failure; HFpEF; Epidemiology; Clinical presentation; Pathophysiology; OBSTRUCTIVE PULMONARY-DISEASE; LEFT-VENTRICULAR HYPERTROPHY; SEX-DIFFERENCES; SYSTOLIC FUNCTION; CO-MORBIDITIES; ADIPOSE-TISSUE; RISK; PREVALENCE; MANAGEMENT; SURVIVAL;

D O I：

10.1093/eurjpc/zwab077

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Heart failure with preserved ejection fraction (HFpEF) is highly prevalent and is associated with relevant morbidity and mortality. However, an evidence-based treatment is still absent. The heterogeneous definitions, differences in aetiology/pathophysiology, and diagnostic challenges of HFpEF made it difficult to define its epidemiological landmarks so far. Several large registries and observational studies have recently disclosed an increasing incidence/prevalence, as well as its prognostic significance. An accurate definition of HFpEF epidemiological boundaries and phenotypes is mandatory to develop novel effective and rational therapeutic approaches.

引用

页码：1233 / 1243

页数：11

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