Instrument response measurements of ion mobility spectrometers in situ: Maintaining optimal system performance of fielded systems

被引:41
作者
Wallis, E [1 ]
Griffin, TM [1 ]
Popkie, N [1 ]
Eagan, MA [1 ]
McAtee, RF [1 ]
Vrazel, D [1 ]
McKinly, J [1 ]
机构
[1] USN, Ctr Surface Warfare, EG&G Tech Serv, Crane Div, Crane, IN 47522 USA
来源
Chemical and Biological Sensing VI | 2005年 / 5795卷
关键词
ion mobility spectroscopy; chemical warfare agent detection; PLASMA CHROMATOGRAPHY;
D O I
10.1117/12.609920
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Ion Mobility Spectroscopy (IMS) is the most widespread detection technique in use by the military for the detection of chemical warfare agents, explosives, and other threat agents. Moreover, its role in homeland security and force protection has expanded due, in part, to its good sensitivity, low power, lightweight, and reasonable cost. With the increased use of IMS systems as continuous monitors, it becomes necessary to develop tools and methodologies to ensure optimal performance over a wide range of conditions and extended periods of time. Namely, instrument calibration is needed to ensure proper sensitivity and to correct for matrix or environmental effects. We have developed methodologies to deal with the semi-quantitative nature of IMS and allow us to generate response curves that allow a gauge of instrument performance and maintenance requirements. This instrumentation communicates to the IMS systems via a software interface that was developed in-house. The software measures system response, logs information to a database, and generates the response curves. This paper will discuss the instrumentation, software, data collected, and initial results from fielded systems.
引用
收藏
页码:54 / 64
页数:11
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