Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum β-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil

被引：53

作者：

Garcia, Doroti de Oliveira ^{[1
,2
]}

Doi, Yohei ^{[1
]}

Szabo, Dora ^{[3
]}

Adams-Haduch, Jennifer M. ^{[1
]}

Vaz, Tania M. I. ^{[2
]}

Leite, Daniela ^{[2
]}

Padoveze, Maria Clara ^{[4
]}

Freire, Maristela P. ^{[4
]}

Silveira, Fernanda P. ^{[1
]}

Paterson, David L. ^{[1
,5
,6
]}

机构：

[1] Univ Pittsburgh, Med Ctr, Div Infect Dis, Pittsburgh, PA 15213 USA

[2] Adolfo Lutz Inst, Sao Paulo, Brazil

[3] Semmelweis Univ, Inst Med Microbiol, H-1085 Budapest, Hungary

[4] Ctr Controle Doencas, Div Infeccao Hosp, Sao Paulo, Brazil

[5] Univ Queensland, Brisbane, Qld, Australia

[6] Royal Brisbane & Womens Hosp, Queensland Hlth Pathol Serv, Brisbane, Qld, Australia

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2008年 / 52卷 / 05期

关键词：

D O I：

10.1128/AAC.01440-07

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

An outbreak of cephalosporin-resistant Klebsiella pneumoniae occurred in a neonatal intensive care unit in Sao Paulo, Brazil. Of the 10 pulsotypes identified during the outbreak and follow-up periods, nine produced CTX-M-2 or its new variant CTX-M-59 and one produced SRV-5. bla(CTX-M-2/59) genes were located on closely related plasmids that were transferable.

引用

页码：1790 / 1793

页数：4

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