Worldwide Alzheimer's Disease Neuroimaging Initiative

被引:78
作者
Carrillo, Maria C. [1 ]
Bain, Lisa J.
Frisoni, Giovanni B. [2 ]
Weiner, Michael W. [3 ,4 ]
机构
[1] Alzheimers Assoc, Med cfc Sci Relat, Chicago, IL USA
[2] IRCCS, Ctr San Giovanni Dio Fatebenefratelli, Lab Neuroimaging, Brescia, Italy
[3] San Francisco VA Med Ctr, No Calif Inst Res, San Francisco, CA USA
[4] Univ Calif San Francisco, Dept Radiol, San Francisco, CA 94143 USA
基金
美国国家卫生研究院;
关键词
Alzheimer's disease; Neuroimaging; Biomarkers; ASSOCIATION WORKGROUPS; DIAGNOSTIC GUIDELINES; NATIONAL INSTITUTE; RECOMMENDATIONS; DISCOVERY; MILD;
D O I
10.1016/j.jalz.2012.04.007
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The Alzheimer's Disease Neuroimaging Initiative (ADNI) was launched in 2003 to speed drug development by validating imaging and blood/cerebrospinal fluid biomarkers for Alzheimer's disease clinical treatment trials. ADNI is a naturalistic (nontreatment) multisite longitudinal study. A true public private partnership, the first phase of ADNI (ADNI 1) set a new standard for data sharing without embargo. In addition, it has been extended to 2017 by additional funding (North American-ADNI Grand Opportunities and ADNI 2) as well as multiple projects around the world, collectively known as Worldwide ADNI (WW-ADNI). The goal of WW-ADNI is to harmonize projects and results across different geographical sites and to encourage and harmonize data management and availability to investigators around the world. WW-ADNI projects are currently underway in North America, Europe, Japan, Australia, Korea, Taiwan, and Argentina, with a nascent program in China and a possible future program in Brazil. (C) 2012 The Alzheimer's Association. All rights reserved.
引用
收藏
页码:337 / 342
页数:6
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