Progress in stem cell therapy for the diabetic foot

被引：27

作者：

Jiang, Xiao-Yan ^{[1
]}

Lu, De-Bin ^{[1
]}

Chen, Bing ^{[1
]}

机构：

[1] Third Mil Med Univ, Southwest Hosp, Dept Endocrinol, Chongqing 400038, Peoples R China

来源：

DIABETES RESEARCH AND CLINICAL PRACTICE | 2012年 / 97卷 / 01期

关键词：

Stem cell; Foot ulcer; Limb ischemia; Diabetes mellitus; Diabetes complications; ENDOTHELIAL PROGENITOR CELLS; CRITICAL LIMB ISCHEMIA; BONE-MARROW-CELLS; ADIPOSE STROMAL CELLS; CORD BLOOD; IN-VIVO; AUTOLOGOUS TRANSPLANTATION; VASCULAR COMPLICATIONS; MONONUCLEAR-CELLS; ARTERIAL-DISEASE;

D O I：

10.1016/j.diabres.2011.12.011

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The diabetic foot is a common and severe complication of diabetes comprising a group of lesions including vasculopathy, neuropathy, tissue damage and infection. Vasculopathy due to ischemia is a major contributor to the pathogenesis, natural history and outcome of the diabetic foot. Despite conventional revascularization interventions including angioplasty, stenting, atherectomy and bypass grafts to vessels, a high incidence of amputation persists. The need to develop alternative therapeutic options is compelling; stem cell therapy aims to increase revascularization and alleviate limb ischemia or improve wound healing by stimulating new blood vessel formation, and brings new hope for the treatment of the diabetic foot. (C) 2011 Elsevier Ireland Ltd. All rights reserved.

引用

页码：43 / 50

页数：8

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