Tablet-based sublingual immunotherapy for respiratory allergy

被引：1

作者：

Prieto, L. ^{[1
,2
]}

机构：

[1] Hosp Dr Peset, Secc Alergol, Valencia, Spain

[2] Univ Valencia, Valencia, Spain

来源：

ALLERGOLOGIA ET IMMUNOPATHOLOGIA | 2017年 / 45卷

关键词：

Allergen immunotherapy; Tablet-based immunotherapy; Sublingual immunotherapy; Asthma; Allergic rhinitis; Respiratory allergy;

D O I：

10.1016/j.aller.2017.09.008

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Allergic respiratory disease represents a significant and expanding health problem worldwide. The gold standard of therapeutic intervention is still grucocorticosteroids, although they are not effective in all patients and may cause side effects. Allergen Immunotherapy has been administrated as subcutaneous injections for treatment of allergic rhinoconjunctivitis and asthma and has been practiced for the past century. Sublingual immunotherapy (SLIT) tablets are now available for grass- or ragweed-induced rhinoconjunctivitis and will be available in Spain for house dust mite (HDM)-induced rhinoconjunctivitis and asthma in the next months. In this review, new developments in the field of tablet-based SLIT for respiratory allergy are summarized, with special emphasis on HDM-induced allergic rhinitis and asthma. SLIT tablets are the best-documented immunotherapy products on the market and represent a more patient friendly concept because they can be self-administrated at home. (C) 2017 SEICAP. Published by Elsevier Espana, S.L.U. All rights reserved.

引用

页码：30 / 35

页数：6

共 27 条

[1]

Cox LS, 2016, J ALLERGY CLIN IMMUN, DOI [10.1016/j.jaci:2016.01.039.20, DOI 10.1016/J.JACI:2016.01.039.20]

[2] Efficacy and safety of sublingual immunotherapy with grass allergen tablets for seasonal allergic rhinoconjunctivitis [J].

Dahl, Ronald ;

Kapp, Alexander ;

Colombo, Giselda ;

deMonchy, Jan G. R. ;

Rak, Sabina ;

Emminger, Waltraud ;

Rivas, Montserrat Fernandez ;

Ribel, Mette ;

Durham, Stephen R. .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2006, 118 (02) :434-440

[3] SQ HDM SLIT-tablet (ALK) in treatment of asthma - Post hoc results from a randomised trial [J].

de Blay, F. ;

Kuna, P. ;

Prieto, L. ;

Ginko, T. ;

Seitzberg, D. ;

Riis, B. ;

Canonica, G. W. .

RESPIRATORY MEDICINE, 2014, 108 (10) :1430-1437

[4] Effective treatment of house dust mite-induced allergic rhinitis with 2 doses of the SQ HDM SLIT-tablet: Results from a randomized, double-blind, placebo-controlled phase III trial [J].

Demoly, Pascal ;

Emminger, Waltraud ;

Rehm, Dorte ;

Backer, Vibeke ;

Tommerup, Lene ;

Kleine-Tebbe, Joerg .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2016, 137 (02) :444-+

[5] A meta-analysis of sublingual allergen immunotherapy and pharmacotherapy in pollen-induced seasonal allergic rhinoconjunctivitis [J].

Devillier, Philippe ;

Dreyfus, Jean-Francois ;

Demoly, Pascal ;

Calderon, Moises A. .

BMC MEDICINE, 2014, 12

[6] Efficacy of Grass Pollen Allergen Sublingual Immunotherapy Tablets for Seasonal Allergic Rhinoconjunctivitis A Systematic Review and Meta-analysis [J].

Di Bona, Danilo ;

Plaia, Antonella ;

Leto-Barone, Maria Stefania ;

La Piana, Simona ;

Di Lorenzo, Gabriele .

JAMA INTERNAL MEDICINE, 2015, 175 (08) :1301-1309

[7] Post-treatment efficacy of discontinuous treatment with 300IR 5-grass pollen sublingual tablet in adults with grass pollen-induced allergic rhinoconjunctivitis [J].

Didier, A. ;

Malling, H. -J. ;

Worm, M. ;

Horak, F. ;

Sussman, G. ;

Melac, M. ;

Soulie, S. ;

Zeldin, R. K. .

CLINICAL AND EXPERIMENTAL ALLERGY, 2013, 43 (05) :568-577

[8] Optimal dose, efficacy, and safety of once-daily sublingual immunotherapy with a 5-grass pollen tablet for seasonal allergic rhinitis [J].

Didier, Alain ;

Malling, Hans-Jorgen ;

Worm, Margitta ;

Horak, Friedrich ;

Jaeger, Siegfried ;

Montagut, Armelle ;

Andre, Claude ;

de Beaumont, Olivier ;

Melac, Michel .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2007, 120 (06) :1338-1345

[9] Sustained 3-year efficacy of pre- and coseasonal 5-grass-pollen sublingual immunotherapy tablets in patients with grass pollen-induced rhinoconjunctivitis [J].

Didier, Alain ;

Worm, Margitta ;

Horak, Friedrich ;

Sussman, Gordon ;

de Beaumont, Olivier ;

Le Gall, Martine ;

Melac, Michel ;

Malling, Hans-Jorgen .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2011, 128 (03) :559-566

[10] Sublingual immunotherapy with once-daily grass allergen tablets: A randomized controlled trial in seasonal allergic rhinoconjunctivitis [J].

Durham, SR ;

Yang, WH ;

Pedersen, MR ;

Johansen, N ;

Rak, S .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2006, 117 (04) :802-809

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