Sequential and domino Sonogashira coupling:: Efficient tools for the synthesis of diarylalkynes

被引：37

作者：

Nagy, A ^{[1
]}

Novák, Z ^{[1
]}

Kotschy, A ^{[1
]}

机构：

[1] Eotvos Lorand Univ, Dept Gen & Inorgan Chem, H-1117 Budapest, Hungary

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2005年 / 690卷 / 20期

关键词：

Sonogashira reaction; cross-coupling; diarylalkynes; palladium;

D O I：

10.1016/j.jorganchem.2004.12.036

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The Sonogashira, coupling reaction of aryl halides with a masked acetylene, leading to the formation of diarylethynes is reviewed. The process is either run in a sequential coupling-deprotection-coupling manner, or sometimes it is carried out in one-pot, a reaction we coined domino coupling. The procedures were also extended to the synthesis Of Compound libraries. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：4453 / 4461

页数：9

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