机构:
Chongqing Med Univ, Dept Pathol, Mol Med & Canc Res Ctr, Chongqing, Peoples R ChinaChongqing Med Univ, Dept Pathol, Mol Med & Canc Res Ctr, Chongqing, Peoples R China
Fauzee, Nilufer Jasmine Selimah
[1
]
Dong, Zhi
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机构:
Chongqing Med Univ, Coll Pharm, Dept Pharmacol, Chongqing, Peoples R ChinaChongqing Med Univ, Dept Pathol, Mol Med & Canc Res Ctr, Chongqing, Peoples R China
Dong, Zhi
[2
]
Wang, Ya-lan
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机构:
Chongqing Med Univ, Dept Pathol, Mol Med & Canc Res Ctr, Chongqing, Peoples R ChinaChongqing Med Univ, Dept Pathol, Mol Med & Canc Res Ctr, Chongqing, Peoples R China
Wang, Ya-lan
[1
]
机构:
[1] Chongqing Med Univ, Dept Pathol, Mol Med & Canc Res Ctr, Chongqing, Peoples R China
[2] Chongqing Med Univ, Coll Pharm, Dept Pharmacol, Chongqing, Peoples R China
Taxanes;
Taxol;
Taxotere;
cancer chemotherapy;
DOCETAXEL-INDUCED APOPTOSIS;
ADVANCED GASTRIC-CANCER;
HUMAN LUNG-CANCER;
SIGNAL-REGULATED KINASE;
FOCAL ADHESION KINASE;
HUMAN PROSTATE-CANCER;
HUMAN-MELANOMA CELLS;
TRANS-RETINOIC ACID;
BREAST-CANCER;
OVARIAN-CANCER;
D O I:
暂无
中图分类号:
R73 [肿瘤学];
学科分类号:
100214 ;
摘要:
Taxanes are amongst the most promising antitumor agents available at hand today, of increasing importance in Asia given that cancer is now one of the major public health problems which needs to be dealt urgently for the benefit of affected patients. Several ongoing experimental and clinical trials have supported the fact that even with their side effects and poor solubilities, taxanes are still the first lines of treatment chosen for breast, ovary, lung and other metastatic cancers. Prolonging the life of cancer patients is the main aim of all researchers, scientists, pharmaceutical companies and clinicians; therefore this review emphasizes the mechanisms of action of taxanes and how they can play an important role in palliative treatment if not applied for curative purposes, hence being considered a boon for cancer management.
机构:
New York Inst Technol, Dept Biomed Sci, Coll Osteopath Med, Old Westbury, NY 11568 USANew York Inst Technol, Dept Biomed Sci, Coll Osteopath Med, Old Westbury, NY 11568 USA
Seltzer, Emily S.
Watters, Andrea K.
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机构:
New York Inst Technol, Dept Biomed Sci, Coll Osteopath Med, Old Westbury, NY 11568 USANew York Inst Technol, Dept Biomed Sci, Coll Osteopath Med, Old Westbury, NY 11568 USA
Watters, Andrea K.
MacKenzie, Danny
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机构:
New York Inst Technol, Dept Biomed Sci, Coll Osteopath Med, Old Westbury, NY 11568 USANew York Inst Technol, Dept Biomed Sci, Coll Osteopath Med, Old Westbury, NY 11568 USA
MacKenzie, Danny
Granat, Lauren M.
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h-index: 0
机构:
Cleveland Clin, Dept Internal Med, Cleveland, OH 44195 USANew York Inst Technol, Dept Biomed Sci, Coll Osteopath Med, Old Westbury, NY 11568 USA
Granat, Lauren M.
Zhang, Dong
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机构:
New York Inst Technol, Dept Biomed Sci, Coll Osteopath Med, Old Westbury, NY 11568 USANew York Inst Technol, Dept Biomed Sci, Coll Osteopath Med, Old Westbury, NY 11568 USA
机构:
Uniwersytet Med K Marcinkowskiego Poznaniu, Zaklad Histol & Embriol, Poznan, Poland
Uniwersytet Zielonogorski, Katedra Anat & Histol, Zielona Gora, PolandUniwersytet Med K Marcinkowskiego Poznaniu, Zaklad Histol & Embriol, Poznan, Poland
Sujka-Kordowska, Patrycja
Kaluzna, Sandra
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h-index: 0
机构:
Uniwersytet Med K Marcinkowskiego Poznaniu, Zaklad Histol & Embriol, Poznan, PolandUniwersytet Med K Marcinkowskiego Poznaniu, Zaklad Histol & Embriol, Poznan, Poland
Kaluzna, Sandra
Malinska, Agnieszka
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h-index: 0
机构:
Uniwersytet Med K Marcinkowskiego Poznaniu, Zaklad Histol & Embriol, Poznan, Poland
Uniwersytet Zielonogorski, Katedra Anat & Histol, Zielona Gora, PolandUniwersytet Med K Marcinkowskiego Poznaniu, Zaklad Histol & Embriol, Poznan, Poland