Application of microarray technology for the analysis of gene expression in veterinary medicine

被引:0
作者
Merk, Sylvia [1 ]
Martin, Dugas [1 ]
机构
[1] Univ Munster, Inst Med Informat & Biomath, D-48149 Munster, Germany
来源
BERLINER UND MUNCHENER TIERARZTLICHE WOCHENSCHRIFT | 2008年 / 121卷 / 5-6期
关键词
gene expression; microarray; veterinary medicine; data analysis; data management;
D O I
10.2376/0005-9366-121-179
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
The establishment of microarray technology enables the analysis of global gene expression in a single experiment. This novel analysis technique is not only used in human medicine but also has found its way into veterinary medicine. This article presents an overview of the underlying technology as well as a description of various data analysis techniques.
引用
收藏
页码:179 / 188
页数:10
相关论文
共 62 条
[1]  
*AFF, 2005, GUID PROB LOG INT ER
[2]   Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays [J].
Alon, U ;
Barkai, N ;
Notterman, DA ;
Gish, K ;
Ybarra, S ;
Mack, D ;
Levine, AJ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (12) :6745-6750
[3]  
[Anonymous], 1993, Resampling-based multiple testing: Examples and methods for P-value adjustment
[4]   Gene Ontology: tool for the unification of biology [J].
Ashburner, M ;
Ball, CA ;
Blake, JA ;
Botstein, D ;
Butler, H ;
Cherry, JM ;
Davis, AP ;
Dolinski, K ;
Dwight, SS ;
Eppig, JT ;
Harris, MA ;
Hill, DP ;
Issel-Tarver, L ;
Kasarskis, A ;
Lewis, S ;
Matese, JC ;
Richardson, JE ;
Ringwald, M ;
Rubin, GM ;
Sherlock, G .
NATURE GENETICS, 2000, 25 (01) :25-29
[5]  
Benjamini Y, 2001, ANN STAT, V29, P1165
[6]   CONTROLLING THE FALSE DISCOVERY RATE - A PRACTICAL AND POWERFUL APPROACH TO MULTIPLE TESTING [J].
BENJAMINI, Y ;
HOCHBERG, Y .
JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY, 1995, 57 (01) :289-300
[7]  
Bishop CM., 1995, Neural networks for pattern recognition
[8]   A comparison of normalization methods for high density oligonucleotide array data based on variance and bias [J].
Bolstad, BM ;
Irizarry, RA ;
Åstrand, M ;
Speed, TP .
BIOINFORMATICS, 2003, 19 (02) :185-193
[9]  
Bonferroni C., 1936, PUBBLICAZIONI R I SU, V8, P3, DOI DOI 10.4135/9781412961288.N455
[10]   Direct identification of chlamydiae from clinical samples using a DNA microarray assay-A validation study [J].
Borel, Nicole ;
Kempf, Evelyne ;
Hotzel, Helmut ;
Schubert, Evelyn ;
Torgerson, Paul ;
Slickers, Peter ;
Ehricht, Ralf ;
Tasara, Taurai ;
Pospischil, Andreas ;
Sachse, Konrad .
MOLECULAR AND CELLULAR PROBES, 2008, 22 (01) :55-64