"Why can't I give you my organs after my heart has stopped beating?" An overview of the main clinical, organisational, ethical and legal issues concerning organ donation after circulatory death in Italy

被引:0
作者
Giannini, Alberto [1 ]
Abelli, Massimo [2 ]
Azzoni, Giampaolo [3 ]
Biancofiore, Gianni [4 ]
Citterio, Franco [5 ]
Geraci, Paolo [6 ]
Latronico, Nicola [7 ,8 ]
Picozzi, Mario [9 ]
Procaccio, Francesco [10 ]
Riccioni, Luigi [11 ]
Rigotti, Paolo [12 ]
Valenza, Franco [13 ]
Vesconi, Sergio [14 ]
Zamperetti, Nereo [15 ]
机构
[1] Fdn IRCCS Ca Granda, Osped Maggiore Policlin, Terapia Intens Pediat, Milan, Italy
[2] Fdn IRCCS Policlin San Matteo, Dipartimento Chirurg, Unita Trapianto Rene, Pavia, Italy
[3] Univ Pavia, Dipartimento Giurisprudenza, Pavia, Italy
[4] Azienda Osped Univ Pisana, SD Anestesia & Rianimaz Trapianto Fegato, Pisa, Italy
[5] Univ Cattolica Sacro Cuore, Dipartimento Sci Chirurg, Policlin A Gemelli, Trapiantol Renale, Rome, Italy
[6] Fdn IRCCS Policlin San Matteo, Ctr Coordinamento Donaz & Trapianti, Pavia, Italy
[7] Univ Brescia, Dipartimento Specialita Med Chirurg Sci Radiol &, I-25121 Brescia, Italy
[8] Azienda Osped Spedali Civili Brescia, Dipartimento Anestesia &Rianimaz Emergenza Urgenz, Brescia, Italy
[9] Univ Insubria, Dipartimento Biotecnol & Sci Vita, Sez Med Legale, Varese, Italy
[10] Ist Super Sanita, Ctr Nazl Trapianti, Rome, Italy
[11] Osped San Camillo Forlanini, Ctr Shock & Trauma, Rome, Italy
[12] Univ Padua, Unita Trapianti Rene & Pancreas, Azienda Osped Padova, Padua, Italy
[13] Univ Milan, Dipartimento Fisiopatol & Trapianti, Fdn IRCCS Ca Granda, Osped Maggiore Policlin, Milan, Italy
[14] Direz Gen Salute, Coordinamento Prelievo Organi & Tessuti, Milan, Italy
[15] Azienda ULSS 6 Vicenza, Serv Qualita Sicurezza & Accreditamento, Vicenza, Italy
关键词
Tissue and organ procurement; Transplantation; Ethics; VIVO LUNG PERFUSION; UNCONTROLLED DONATION; BRAIN-DEATH; TRANSPLANTATION; PROCUREMENT; PROTOCOLS; DECISIONS; INCREASE; NUMBER; DONORS;
D O I
暂无
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Donation after circulatory death (DCD) is a valuable option for the procurement of functioning organs for transplantation. Clinical results are promising and public acceptance is quite good in most western countries. Yet, although DCD is widespread in Europe, several problems still persist in Italy as well as in some other countries. This paper aims to describe the main clinical, organisational, ethical and legal issues at stake, bearing in mind the particular situation created by Italian legislation. Currently, as regards DCD, Italy is somewhat different from other countries. Therefore, every effort should be made for the safe and effective implementation of DCD programs: uncontrolled DCD programs should be promoted and encouraged, within the framework of shared and authoritative rules. At the same time, we need to tackle the question of controlled DCD, promoting debate among all involved subjects regarding the fundamental issues of end-of-life care within protocols that best integrate the highest standard of care for the dying and the legitimate interests of those awaiting a life-saving organ.
引用
收藏
页码:359 / 368
页数:10
相关论文
共 43 条
[1]  
[Anonymous], 2011, Transplantation, V91 Suppl 11, pS29, DOI 10.1097/01.tp.0000399131.74618.a5
[2]   DECISIONS TO LIMIT OR CONTINUE LIFE-SUSTAINING TREATMENT BY CRITICAL CARE PHYSICIANS IN THE UNITED-STATES - CONFLICTS BETWEEN PHYSICIANS PRACTICES AND PATIENTS WISHES [J].
ASCH, DA ;
HANSENFLASCHEN, J ;
LANKEN, PN .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1995, 151 (02) :288-292
[3]   An International Comparison of the Effect of Policy Shifts to Organ Donation following Cardiocirculatory Death (DCD) on Donation Rates after Brain Death (DBD) and Transplantation Rates [J].
Bendorf, Aric ;
Kelly, Patrick J. ;
Kerridge, Ian H. ;
McCaughan, Geoffrey W. ;
Myerson, Brian ;
Stewart, Cameron ;
Pussell, Bruce A. .
PLOS ONE, 2013, 8 (05)
[4]   Report of a national conference on donation after cardiac death [J].
Bernat, JL ;
D'Alessandro, AM ;
Port, FK ;
Bleck, TP ;
Heard, SO ;
Medina, J ;
Rosenbaum, SH ;
DeVita, MA ;
Gaston, RS ;
Merion, RM ;
Barr, ML ;
Marks, WH ;
Nathan, H ;
O'Connor, K ;
Rudow, DL ;
Leichtman, AB ;
Schwab, P ;
Ascher, NL ;
Metzger, RA ;
Mc Bride, V ;
Graham, W ;
Wagner, D ;
Warren, J ;
Delmonico, FL .
AMERICAN JOURNAL OF TRANSPLANTATION, 2006, 6 (02) :281-291
[5]   End-of-life decision-making and quality of ICU performance: an observational study in 84 Italian units [J].
Bertolini, Guido ;
Boffelli, Simona ;
Malacarne, Paolo ;
Peta, Mario ;
Marchesi, Mariano ;
Barbisan, Camillo ;
Tomelleri, Stefano ;
Spada, Simonetta ;
Satolli, Roberto ;
Gridelli, Bruno ;
Lizzola, Ivo ;
Mazzon, Davide .
INTENSIVE CARE MEDICINE, 2010, 36 (09) :1495-1504
[6]   Cost-Effectiveness of Kidney Transplantation From DCD in Italy [J].
Cavallo, M. G. ;
Sepe, V. ;
Conte, F. ;
Abelli, M. ;
Ticozzelli, E. ;
Bottazzi, A. ;
Geraci, P. M. .
TRANSPLANTATION PROCEEDINGS, 2014, 46 (10) :3289-3296
[7]  
Comitato Nazionale per la Bioetica, 2010, CRIT ACC MORT
[8]  
Council of Europe, 2014, NEWSLETTER TRANSPLAN
[9]   Normothermic Ex Vivo Lung Perfusion in Clinical Lung Transplantation [J].
Cypel, Marcelo ;
Yeung, Jonathan C. ;
Liu, Mingyao ;
Anraku, Masaki ;
Chen, Fengshi ;
Karolak, Wojtek ;
Sato, Masaaki ;
Laratta, Jane ;
Azad, Sassan ;
Madonik, Mindy ;
Chow, Chung-Wai ;
Chaparro, Cecilia ;
Hutcheon, Michael ;
Singer, Lianne G. ;
Slutsky, Arthur S. ;
Yasufuku, Kazuhiro ;
de Perrot, Marc ;
Pierre, Andrew F. ;
Waddell, Thomas K. ;
Keshavjee, Shaf .
NEW ENGLAND JOURNAL OF MEDICINE, 2011, 364 (15) :1431-1440
[10]   Adult heart transplantation with distant procurement and ex-vivo preservation of donor hearts after circulatory death: a case series [J].
Dhital, Kumud K. ;
Iyer, Arjun ;
Connellan, Mark ;
Chew, Hong C. ;
Gao, Ling ;
Doyle, Aoife ;
Hicks, Mark ;
Kumarasinghe, Gayathri ;
Soto, Claude ;
Dinale, Andrew ;
Cartwright, Bruce ;
Nair, Priya ;
Granger, Emily ;
Jansz, Paul ;
Jabbour, Andrew ;
Kotlyar, Eugene ;
Keogh, Anne ;
Hayward, Christopher ;
Graham, Robert ;
Spratt, Phillip ;
Macdonald, Peter .
LANCET, 2015, 385 (9987) :2585-2591