A review on recent applications of deep eutectic solvents in microextraction techniques for the analysis of biological matrices

被引：45
作者：
de Andrade, Debora Coelho [1 ,3 ]
Monteiro, Sofia Aquino [1 ]
Merib, Josias [1 ,2 ,3 ,4 ]
机构：
[1] Univ Fed Ciencias Saude Porto Alegre, BR-90050170 Porto Alegre, RS, Brazil
[2] Univ Fed Ciencias Saude Porto Alegre, Dept Farmacociencias, BR-90050170 Porto Alegre, RS, Brazil
[3] Univ Fed Ciencias Saude Porto Alegre, Programa Posgrad Biociencias, Inst Ciencias Basicas Saude, BR-90050170 Porto Alegre, RS, Brazil
[4] 245 Sarmento Leite St, BR-90050170 Porto Alegre, RS, Brazil
来源：
ADVANCES IN SAMPLE PREPARATION | 2022年 / 1卷
关键词：
Deep eutectic solvents; Microextraction; Sample preparation; Biological matrices; LIQUID-LIQUID MICROEXTRACTION; PHASE MICROEXTRACTION; ANALYTICAL-CHEMISTRY; EXTRACTION; PRECONCENTRATION; URINE; WATER; METHADONE; CHLORIDE;
D O I：
10.1016/j.sampre.2022.100007
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
In general, the analysis of biological matrices is challenging and a sample preparation step employing extraction/cleanup techniques is required. Liquid-phase microextraction using deep eutectic solvents has been exploited in numerous applications because these solvents exhibit fascinating physico-chemical properties in addition to simple and straightforward preparation. Varied configurations and strategies have been examined for the determination of different classes of analytes, and these methodologies offer environmentally friendly workflows with low solvent and sample consumption, rapid and simple experimental procedures, and satisfactory analytical performance. In this review, developments related to the use of deep eutectic solvents in microextraction approaches for the analysis of biological matrices are briefly discussed with a focus on studies reported from 2017 to 2021.
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页数：10
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