Synthesis of Cyclobutanones by Gold(I)-Catalyzed [2+2] Cycloaddition of Ynol Ethers with Alkenes

被引：12
|
作者：
Zanini, Margherita [1 ,2 ]
Cataffo, Andrea [1 ,2 ]
Echavarren, Antonio M. [1 ,2 ]
机构：
[1] Barcelona Inst Sci & Technol, Inst Chem Res Catalonia ICIQ, Tarragona 43007, Spain
[2] Univ Rovira & Virgili, Dept Quim Analit & Quim Organ, Tarragona 43007, Spain
来源：
ORGANIC LETTERS | 2021年 / 23卷 / 22期
关键词：
HALOGENATED KETENES; SCALABLE SYNTHESIS; RING EXPANSION; ALKYNES; CYCLOBUTENE;
D O I：
10.1021/acs.orglett.1c03499
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A broad scope synthesis of cyclobutanones by gold(I)-catalyzed [2 + 2] cycloaddition of ynol ethers with alkenes has been developed. We also found that internal aryl ynol ethers can undergo (4 + 2) cycloaddition reaction with alkenes leading to the corresponding chromanes.
引用
收藏
页码：8989 / 8993
页数：5
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