Lipid-based nanocarriers for breast cancer treatment - comprehensive review

被引：82

作者：

Talluri, Siddartha Venkata ^{[1
]}

Kuppusamy, Gowthamarajan ^{[1
]}

Karri, Veera Venkata Satyanarayana Reddy ^{[1
]}

Tummala, Shashank ^{[1
]}

Madhunapantula, SubbaRao V. ^{[2
]}

机构：

[1] JSS Univ, JSS Coll Pharm, Dept Pharmaceut, Udhagamandalam 643001, Tamil Nadu, India

[2] JSS Univ, JSS Med Coll, Dept Biochem, Mysore, Karnataka, India

来源：

DRUG DELIVERY | 2016年 / 23卷 / 04期

关键词：

Breast cancer; lipid; lipid polymer hybrid nanoparticles; liposomes; nanostructured lipid carriers; solid lipid nanoparticles; POLYMER HYBRID NANOPARTICLES; DRUG-DELIVERY SYSTEM; SURGICAL ADJUVANT BREAST; IN-VITRO; MULTIDRUG-RESISTANCE; LIPOSOMAL DOXORUBICIN; THERAPEUTIC DELIVERY; ANTITUMOR-ACTIVITY; CELLULAR UPTAKE; CELLS;

D O I：

10.3109/10717544.2015.1092183

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Breast cancer is the second leading cancer-related disease as the most common non-cutaneous malignancy among women. Curative options for breast cancer are limited, therapeutically substantial and associated with toxicities. Emerging nanotechnologies exhibited the possibility to treat or target breast cancer. Among the nanoparticles, various lipid nanoparticles namely, liposomes, solid lipid nanoparticles, nanostructured lipid carriers and lipid polymer hybrid nanoparticles have been developed over the years for the breast cancer therapy and evidences are documented. Concepts are confined in lab scale, which needs to be transferred to large scale to develop active targeting nanomedicine for the clinical utility. So, the present review highlights the recently published studies in the development of lipid-based nanocarriers for breast cancer treatment.

引用

页码：1291 / 1305

页数：15

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