Extensions of the Icosahedral Closomer Structure by Using Azide-Alkyne Click Reactions

被引：16

作者：

Goswami, Lalit N. ^{[1
]}

Chakravarty, Shatadru ^{[2
]}

Lee, Mark W. ^{[1
]}

Jalisatgi, Satish S. ^{[1
]}

Hawthorne, M. Frederick ^{[1
]}

机构：

[1] Univ Missouri, Sch Med, Int Inst Nano & Mol Med, Columbia, MO 65211 USA

[2] Univ Missouri, Dept Chem, Columbia, MO 65211 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 20期

关键词：

click chemistry; closomers; clusters; esterification; polyhedral boranes; NEUTRON-CAPTURE THERAPY; POLYHEDRAL BORANES; B12H12-2; ION; CHEMISTRY; DERIVATIVES; B10H10-2; ANIONS; CANCER;

D O I：

10.1002/anie.201101066

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Clusters with a click: The chemistry of icosahedral borane closomers has been combined with click chemistry for the first time. This approach provided a facile syntheses of diverse 12-fold closomer nanoparticles (see scheme; R=alkyl or aryl) which could be adapted for biomedical and material applications. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：4689 / 4691

页数：3

共 38 条

[1] An improved method for the synthesis of [closo-B12(OH)12]-2 [J].

Bayer, MJ ;

Hawthorne, MF .

INORGANIC CHEMISTRY, 2004, 43 (06) :2018-2020

[2] Synthesis of stable dodecaalkoxy derivatives of hypercloso-B12H12 [J].

Farha, OK ;

Julius, RL ;

Lee, MW ;

Huertas, RE ;

Knobler, CB ;

Hawthorne, MF .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (51) :18243-18251

[3] SYNTHESIS OF S-ALKYL AND S-ACYL DERIVATIVES OF MERCAPTOUNDECAHYDRODODECABORATE, A POSSIBLE BORON CARRIER FOR NEUTRON-CAPTURE THERAPY [J].

GABEL, D ;

MOLLER, D ;

HARFST, S ;

ROSLER, J ;

KETZ, H .

INORGANIC CHEMISTRY, 1993, 32 (11) :2276-2278

[4]

Hawthorne M. F, 1993, ANGEW CHEM, V105, P997

[5] Applications of radiolabeled boron clusters to the diagnosis and treatment of cancer [J].

Hawthorne, MF ;

Maderna, A .

CHEMICAL REVIEWS, 1999, 99 (12) :3421-3434

[6]

Hawthorne MF, 2006, ACS SYM SER, V917, P312

[7] Electrical or photocontrol of the rotary motion of a metallacarborane [J].

Hawthorne, MF ;

Zink, JI ;

Skelton, JM ;

Bayer, MJ ;

Liu, C ;

Livshits, E ;

Baer, R ;

Neuhauser, D .

SCIENCE, 2004, 303 (5665) :1849-1851

[8] THE ROLE OF CHEMISTRY IN THE DEVELOPMENT OF BORON NEUTRON-CAPTURE THERAPY OF CANCER [J].

HAWTHORNE, MF .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1993, 32 (07) :950-984

[9] METALLOCARBORANES THAT EXHIBIT NOVEL CHEMICAL FEATURES - VIRTUALLY UNLIMITED VARIETY OF STRUCTURAL AND DYNAMIC FEATURES ARE OBSERVED IN METALLOCARBORANE CHEMISTRY [J].

HAWTHORNE, MF ;

DUNKS, GB .

SCIENCE, 1972, 178 (4060) :462-+

[10] Synthesis and evaluation of transthyretin amyloidosis inhibitors containing carborane pharmacophores [J].

Julius, Richard L. ;

Farha, Omar K. ;

Chiang, Janet ;

Perry, L. Jeanne ;

Hawthorne, M. Frederick .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (12) :4808-4813

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