Gender Differences in Chronic Kidney Disease: Underpinnings and Therapeutic Implications

被引：102
作者：
Carrero, Juan Jesus [1 ,2 ,3 ]
机构：
[1] Karolinska Inst, Div Renal Med, Dept Clin Sci Intervent & Technol, Ctr Mol Med, Stockholm, Sweden
[2] Karolinska Inst, Div Baxter Novum, Dept Clin Sci Intervent & Technol, Ctr Mol Med, Stockholm, Sweden
[3] Karolinska Inst, Ctr Gender Med, Stockholm, Sweden
来源：
KIDNEY & BLOOD PRESSURE RESEARCH | 2010年 / 33卷 / 05期
关键词：
Compliance; Estrogen; Testosterone; HORMONE REPLACEMENT THERAPY; CORONARY-HEART-DISEASE; STAGE RENAL-DISEASE; QUALITY-OF-LIFE; SEX-DIFFERENCES; ARTERIOVENOUS-FISTULA; HEMODIALYSIS-PATIENTS; RISK-FACTORS; POSTMENOPAUSAL WOMEN; CARDIOVASCULAR-DISEASE;
D O I：
10.1159/000320389
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
In nephrology, gender differences exist with regard to the epidemiology, evolution and prognosis of chronic kidney disease (CKD). In some cases, these differences run contrary to the general population trends. This review discusses such gender and sex disparities, including differing impact of traditional and novel risk factors, prescription patterns, differences in the responses to therapies, as well as hormonal factors, all of them potentially influencing propensity, progression and biochemical and psychological aspects of CKD. Through the integration of gender aspects in CKD research and management, we may be able not only to identify novel therapeutic targets but also improve existing treatment options. Copyright (C) 2010 S. Karger AG, Basel
引用
收藏
页码：383 / 392
页数：10
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