Epidemiology of hip fractures in Austria: evidence for a change in the secular trend

被引:71
作者
Dimai, H. P. [1 ]
Svedbom, A. [5 ,6 ]
Fahrleitner-Pammer, A. [1 ]
Pieber, T. [1 ]
Resch, H. [2 ]
Zwettler, E. [3 ]
Chandran, M. [4 ]
Borgstrom, F. [5 ,6 ]
机构
[1] Med Univ Graz, Div Endocrinol & Nucl Med, Dept Internal Med, A-8036 Graz, Austria
[2] St Vincent Hosp, Dept Med 2, Vienna, Austria
[3] Hanusch Hosp Vienna, Ludwig Boltzmann Inst Osteol, Vienna, Austria
[4] Singapore Gen Hosp, Dept Endocrinol, Singapore 0316, Singapore
[5] I3 Innovus, Stockholm, Sweden
[6] Karolinska Inst, Med Management Ctr, Stockholm, Sweden
关键词
Age-adjusted incidence; Crude incidence; Hip fracture; Osteoporosis; Trend analyses; OSTEOPOROTIC FRACTURES; METAANALYSIS; REVERSAL; RATES; WOMEN; RISK;
D O I
10.1007/s00198-010-1271-9
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Hip fracture incidence rates in Austria over a period of 20 years (1989-2008) were assessed. Age-standardized incidence rates increased until 2005 but decreased thereafter. This change in the secular trend was primarily driven by a decrease in hip fracture incidence in women. The aim of the prevailing study was to assess the incidence rates of hip fractures including changes in trend in the Austrian population over a period of 20 years (1989-2008). The number of hip fractures was obtained from the Austrian Hospital Discharge Register for the entire population a parts per thousand yen50 years of age. A correction factor for multiple registrations of the same diagnosis was determined. Incidence rates (cases per 100,000) of hip fracture were calculated in 5-year age intervals. To analyze the overall change in hip fracture for the period, average annual change expressed as incidence rate ratios (IRRs) was calculated. The age-standardized incidence in women increased until 2005, from 493 to 642, and decreased thereafter. In men, it increased at a measured pace until 2006, from 192 to 280, and decreased thereafter with a slight rebound in 2008. The age-standardized incidence in the entire population increased until 2005, from 376 to 496, and decreased thereafter. The IRR for the last 3 years (2006-2008) was significantly below the IRR for the first 17 years (0.94, rho < 0.01), driven by a lower IRR in women (0.91, rho < 0.01) and to a lesser extent by a lower IRR (not statistically significant) in men (0.96, rho < 0.15). The present study indicates that since 2006, age-standardized incidence of hip fractures has been declining in the Austrian population aged 50 years and above. This reversal in the secular trend has primarily been driven by a decrease in hip fracture incidence in women.
引用
收藏
页码:685 / 692
页数:8
相关论文
共 24 条
  • [1] Declining incidence of hip fractures and the extent of use of anti-osteoporotic therapy in Denmark 1997-2006
    Abrahamsen, B.
    Vestergaard, P.
    [J]. OSTEOPOROSIS INTERNATIONAL, 2010, 21 (03) : 373 - 380
  • [2] Incidence of hip fracture over a 10-year period (1991-2000): Reversal of a secular trend
    Chevalley, T.
    Guilley, E.
    Herrmann, F. R.
    Hoffineyer, P.
    Rapin, C.-H.
    Rizzoli, R.
    [J]. BONE, 2007, 40 (05) : 1284 - 1289
  • [3] HIP-FRACTURES IN THE ELDERLY - A WORLDWIDE PROJECTION
    COOPER, C
    CAMPION, G
    MELTON, LJ
    [J]. OSTEOPOROSIS INTERNATIONAL, 1992, 2 (06) : 285 - 289
  • [4] COOPER C, 2009, OSTEOPOROSIS INT, V20, pPL4
  • [5] Epidemiology and outcomes of osteoporotic fractures
    Cummings, SR
    Melton, LJ
    [J]. LANCET, 2002, 359 (9319) : 1761 - 1767
  • [6] Body mass index as a predictor of fracture risk:: A meta-analysis
    De Laet, C
    Kanis, JA
    Odén, A
    Johanson, H
    Johnell, O
    Delmas, P
    Eisman, JA
    Kroger, H
    Fujiwara, S
    Garnero, P
    McCloskey, EV
    Mellstrom, D
    Melton, LJ
    Meunier, PJ
    Pols, HAP
    Reeve, J
    Silman, A
    Tenenhouse, A
    [J]. OSTEOPOROSIS INTERNATIONAL, 2005, 16 (11) : 1330 - 1338
  • [7] Fragility fractures and the osteoporosis care gap: An international phenomenon
    Giangregorio, L
    Papaioannou, A
    Cranney, A
    Zytaruk, N
    Adachi, JD
    [J]. SEMINARS IN ARTHRITIS AND RHEUMATISM, 2006, 35 (05) : 293 - 305
  • [8] Time trends of age-adjusted incidence rates of first hip fractures: A register-based study among older people in Viborg County, Denmark, 1987-1997
    Giversen, IM
    [J]. OSTEOPOROSIS INTERNATIONAL, 2006, 17 (04) : 552 - 564
  • [9] Greater first year effectiveness drives favorable cost-effectiveness of brand risedronate versus generic or brand alendronate: modeled Canadian analysis
    Grima, D. T.
    Papaioannou, A.
    Thompson, M. F.
    Pasquale, M. K.
    Adachi, J. D.
    [J]. OSTEOPOROSIS INTERNATIONAL, 2008, 19 (05) : 687 - 697
  • [10] Reversal of the hip fracture secular trend is related to a decrease in the incidence in institution-dwelling elderly women
    Guilley, E.
    Chevalley, T.
    Herrmann, F.
    Baccino, D.
    Hoffmeyer, P.
    Rapin, C. -H.
    Rizzoli, R.
    [J]. OSTEOPOROSIS INTERNATIONAL, 2008, 19 (12) : 1741 - 1747