Chitosan nanocomposites based on distinct inorganic fillers for biomedical applications

被引：51

作者：

Moura, Duarte ^{[1
,2
,3
]}

Mano, Joao F. ^{[1
,2
]}

Paiva, Maria C. ^{[3
]}

Alves, Natlia M. ^{[1
,2
]}

机构：

[1] Univ Minho, Headquarters European Inst Excellence Tissue Engn, 3Bs Res Grp Biomat Biodegradables & Biomimet, Guimaraes, Portugal

[2] ICVS 3Bs, Associate PT Govt Lab Braga, Guimaraes, Portugal

[3] Univ Minho, Inst Polymers & Composites I3 N, Dept Polymer Engn, Guimaraes, Portugal

来源：

SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS | 2016年 / 17卷 / 01期

关键词：

Chitosan; polymer nanocomposites; biomedical applications; WALLED CARBON NANOTUBES; IN-VITRO CHARACTERIZATION; REDUCED GRAPHENE OXIDE; MECHANICAL-PROPERTIES; SILICATE NANOCOMPOSITES; THERMAL-CONDUCTIVITY; DRUG-DELIVERY; ELECTROCHEMICAL DETECTION; POLYMER NANOCOMPOSITES; COMPOSITE-MATERIALS;

D O I：

10.1080/14686996.2016.1229104

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Chitosan (CHI), a biocompatible and biodegradable polysaccharide with the ability to provide a non-protein matrix for tissue growth, is considered to be an ideal material in the biomedical field. However, the lack of good mechanical properties limits its applications. In order to overcome this drawback, CHI has been combined with different polymers and fillers, leading to a variety of chitosan-based nanocomposites. The extensive research on CHI nanocomposites as well as their main biomedical applications are reviewed in this paper. An overview of the different fillers and assembly techniques available to produce CHI nanocomposites is presented. Finally, the properties of such nanocomposites are discussed with particular focus on bone regeneration, drug delivery, wound healing and biosensing applications. [GRAPHICS]

引用

页码：626 / 643

页数：18

共 193 条

[1] Modified Chitosan-Clay Nanocomposite as a Drug Delivery System Intercalation and In Vitro Release of Ibuprofen [J].