Doxapram and developmental delay at 12 months in children born extremely preterm

被引:17
作者
Lando, A [1 ]
Klamer, A [1 ]
Jonsbo, F [1 ]
Weiss, J [1 ]
Greisen, G [1 ]
机构
[1] Copenhagen Univ Hosp, Dept Neonatol, Juliane Marie Ctr, Rigshosp, Copenhagen, Denmark
关键词
developmental delay; doxapram; extremely preterm;
D O I
10.1080/08035250500254449
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Aim: To examine the relation of doxapram to a developmental score achieved by a structured telephone interview in a group of extremely-preterm-born children. Methods: Parents of 88 children born extremely preterm were contacted by telephone and interviewed by a structured questionnaire (R-PDQ) when the corrected age of their child was 9-15 mo. Results: We found that doxapram treatment was associated with a deficit in age-adjusted R-PDQ score. Conclusion: Doxapram may have a negative effect on neurodevelopmental outcome.
引用
收藏
页码:1680 / 1681
页数:2
相关论文
共 7 条
[1]  
GLASCOE FP, 1995, PEDIATRICS, V95, P829
[2]   Parental and professional agreement in developmental assessment of very-low-birthweight and term infants [J].
Heiser, A ;
Curcin, O ;
Luhr, C ;
Grimmer, I ;
Metze, B ;
Obladen, M .
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 2000, 42 (01) :21-24
[3]   Validation of a parent report measure of cognitive development in very preterm infants [J].
Johnson, S ;
Marlow, N ;
Wolke, D ;
Davidson, L ;
Marston, L ;
O'Hare, A ;
Peacock, J ;
Schulte, J .
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 2004, 46 (06) :389-397
[4]  
LANDO A, 2005, IN PRESS ACTA PA MAY
[5]   Effect of doxapram on episodes of apnoea, bradycardia and hypoxaemia in preterm infants [J].
Poets, CF ;
Darraj, S ;
Bohnhorst, B .
BIOLOGY OF THE NEONATE, 1999, 76 (04) :207-213
[6]   Isolated mental developmental delay in very low birth weight infants: Association with prolonged doxapram therapy for apnea [J].
Sreenan, C ;
Etches, PC ;
Demianczuk, N ;
Robertson, CMT .
JOURNAL OF PEDIATRICS, 2001, 139 (06) :832-837
[7]  
THORNTON SM, 1992, ENTWICKLUNGSDIAGNOST, P32