Incidentally Discovered Osseous Metaplasia Within High-grade Urothelial Carcinoma of the Bladder

被引:7
作者
Dudley, Anne G. [1 ]
Tomaszewski, Jeffrey J. [1 ]
Hughes, Amber H. [1 ]
Davies, Benjamin J. [1 ]
机构
[1] Univ Pittsburgh, Med Ctr, Dept Urol, Sch Med, Pittsburgh, PA 15213 USA
关键词
D O I
10.1016/j.urology.2011.06.043
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
A 66-year-old male presented with gross hematuria and acute renal failure secondary to bilateral ureteral obstruction. Further work-up revealed muscle invasive urothelial carcinoma. Pathologic examination following radical cystoprostatectomy revealed high grade urothelial carcinoma with focal tumor-associated stromal osseous metaplasia. Reactive bone formation within urothelial carcinoma is a very rare clinical entity. Although typically benign, the presence of mature bone elements warrants thorough examination for sarcomatoid components. UROLOGY 79: e59-e60, 2012. (C) 2012 Elsevier Inc.
引用
收藏
页码:E59 / E60
页数:2
相关论文
共 6 条
[1]   Sarcomatoid Carcinoma of the Urinary Bladder: The Final Common Pathway of Urothelial Carcinoma Dedifferentiation [J].
Cheng, Liang ;
Zhang, Shaobo ;
Alexander, Riley ;
MacLennan, Gregory T. ;
Hodges, Kurt B. ;
Harrison, Beth T. ;
Lopez-Beltran, Antonio ;
Montironi, Rodolfo .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2011, 35 (05) :E34-E46
[2]   STROMAL OSSEOUS METAPLASIA IN CARCINOMA OF THE BLADDER [J].
EBLE, JN ;
YOUNG, RH .
JOURNAL OF UROLOGY, 1991, 145 (04) :823-825
[3]  
Lamm K., 1995, J UROL PATHOL, V3, P255
[4]   Histologic variants of urothelial carcinoma: differential diagnosis and clinical implications [J].
Lopez-Beltran, Antonio ;
Cheng, Liang .
HUMAN PATHOLOGY, 2006, 37 (11) :1371-1388
[5]   ADENOCARCINOMA OF THE URACHUS SHOWING EXTENSIVE CALCIFICATION AND STROMAL OSSEOUS METAPLASIA [J].
LOPEZBELTRAN, A ;
NOGALES, F ;
DONNE, CH ;
SAYAG, JL .
UROLOGIA INTERNATIONALIS, 1994, 53 (02) :110-113
[6]   Transitional carcinoma of the ureter with osseous metaplasia of the stroma: a case report [J].
Mege-Lechevallier, Florence ;
Cherasse, Arnaud ;
Ronze, Sebastien ;
Colombel, Marc ;
Scoazec, Jean-Yves .
ANNALES DE PATHOLOGIE, 2007, 27 (01) :43-46