Gene polymorphism ACTN3 and ACE in selected gymnasts in Brazil and Japan

被引：6

作者：

Joao, Andrea Ferreira ^{[1
]}

Caniuqueo Vargas, Alexis ^{[2
]}

Hernandez Mosqueira, Claudio ^{[3
]}

da Silva, Sandro Fernandes ^{[4
]}

Izquierdo, Mikel ^{[5
]}

Silva Mella, Hector ^{[6
]}

Ramirez-Campillo, Rodrigo ^{[7
]}

Fernandes Filho, Jose ^{[8
]}

机构：

[1] Univ Fed Rio de Janeiro, Rio De Janeiro, Brazil

[2] Univ Autonoma Chile, Lab Fisiol & Biomecan, Temuco, Chile

[3] Univ Pedro de Valdivia, Pedag Educ Fis, Chillan, Chile

[4] Univ Fed Lavras, Lavras, Brazil

[5] Univ Publ Navarra, Dept Ciencias Salud, Navarra, Spain

[6] Univ La Frontera, Temuco, Chile

[7] Univ Los Lagos, Dept Phys Act Sci, Osorno, Chile

[8] Univ Fed Rio de Janeiro, EEFD, Lab Biociencias Movimiento Humano, Rio De Janeiro, Brazil

来源：

INTERNATIONAL JOURNAL OF MORPHOLOGY | 2015年 / 33卷 / 01期

关键词：

Polymorphism; Angiotensin converting enzyme; a-actinin-3; Sport performance; R577X POLYMORPHISM; ATHLETIC PERFORMANCE; MUSCLE PHENOTYPES; POWER; GENOTYPES; ASSOCIATION; STRENGTH; WOMEN; PLAYERS; ALLELE;

D O I：

10.4067/S0717-95022015000100041

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

In the field of competitive sport, genetics has gained a fundamental role in the study of sport performance. The aim of this study was to analyze the prevalence of polymorphisms R577X and insertion/deletion (I/D), occurring in a-actinin-3 (ACTN3) and angiotensin converting enzyme (ACE) genes, respectively, in Brazilian and Japanese gymnasts. A suitable non-probabilistic sample of 73 gymnasts (14 from Japan) was recruited and signed an informed consent. To measure ACTN3 and ECA saliva samples were obtained by means of real time polymerase chain reaction (iQ5 Thermal Cycler, BioRad). A high prevalence of RXACTN3 genotype, R allele, ACE I/D genotype, and D allele were observed in Brazilian and Japanese gymnasts. In conclusion a high prevalence of RXACTN3 genotype, R allele and ACE I/D genotype would allow a genetic advantage regarding muscle strength and power, possibly facilitating competitive success in gymnastics.

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收藏

页码：262 / 266

页数：5

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