Emissive terbium probe for multiphoton in vitro cell imaging

被引：99

作者：

Law, Ga-Lai ^{[1
,2
]}

Wong, Ka-Leung ^{[4
]}

Man, Cornelia Wing-Yin ^{[3
]}

Wong, Wing-Tak ^{[1
,2
]}

Tsao, Sai-Wah ^{[3
]}

Lam, Michael Hon-Wah ^{[4
]}

Lam, Paul Kwan-Sing ^{[4
]}

机构：

[1] Univ Hong Kong, Dept Chem, Hong Kong, Hong Kong, Peoples R China

[2] Univ Hong Kong, Inst Mol Technol Drug Discovery & Synth, Open Lab Chem Biol, Hong Kong, Hong Kong, Peoples R China

[3] Univ Hong Kong, Dept Anat, Hong Kong, Hong Kong, Peoples R China

[4] City Univ Hong Kong, Dept Biol & Chem, Kowloon Tong, Hong Kong, Peoples R China

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 130卷 / 12期

关键词：

D O I：

10.1021/ja710418d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A polymeric terbium complex that can be excited by near-infrared excitation at 800 nm via multiphoton absorption processes has been synthesized. This complex has been demonstrated to show strong, observable, three-photon-induced f-f emission in cell imaging. In vitro studies carried out in three carcinoma cell lines (A549, HONE1, and HeLa) have been performed and shown to have low cytotoxicity. This complex is therefore a potential candidate for future infrared excitation imaging dyes.

引用

页码：3714 / +

页数：3

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