Acute Rejection and Antibody-Mediated Rejection in Lung Transplantation

被引：25

作者：

Hachem, Ramsey R. ^{[1
]}

机构：

[1] Washington Univ, Sch Med, Div Pulm & Crit Care, 4523 Clayton Ave,Campus Box 8052, St Louis, MO 63110 USA

来源：

CLINICS IN CHEST MEDICINE | 2017年 / 38卷 / 04期

关键词：

Lung transplantation; Acute rejection; Antibody-mediated rejection; Lymphocytic bronchiolitis; BRONCHIOLITIS-OBLITERANS-SYNDROME; ACUTE CELLULAR REJECTION; REFRACTORY ACUTE REJECTION; DONOR-SPECIFIC ANTIBODIES; MINIMAL ACUTE REJECTION; SURVEILLANCE BRONCHOSCOPY; HYPERACUTE REJECTION; WORKING FORMULATION; ALLOGRAFT-REJECTION; HEART-LUNG;

D O I：

10.1016/j.ccm.2017.07.008

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Despite advances in immunosuppression over the past 25 years, acute cellular rejection remains a common complication early after lung transplantation. Although acute cellular rejection has often not resulted in clinical signs or symptoms of allograft dysfunction, it has been widely recognized as a strong independent risk factor for the development of chronic rejection, emphasizing its clinical significance. In recent years, the role of humoral immunity in lung rejection has been increasingly appreciated, and antibody-mediated rejection is now recognized as a form of rejection that may result in allograft failure.

引用

页码：667 / +

页数：10

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