Protein Fouling Characteristics of Graphene Oxide Membranes

被引:6
|
作者
Rode, Richard [1 ]
Schmid, Michael [1 ]
Moghaddam, Saeed [1 ]
机构
[1] Univ Florida, Dept Mech Engn, Gainesville, FL 32611 USA
来源
ADVANCED MATERIALS INTERFACES | 2022年 / 9卷 / 04期
基金
美国国家卫生研究院;
关键词
2D materials; dialyzer; graphene oxide; membranes; protein fouling; NANOFILTRATION MEMBRANE; COMPOSITE FILMS; ADSORPTION; ULTRAFILTRATION; SURFACE; FLUX; MICROFILTRATION; HYDROPHILICITY; PERFORMANCE; NANOSHEETS;
D O I
10.1002/admi.202101613
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Advancing the knowledge of surfaces and protein interactions is paramount to development of non-fouling membranes for many applications, particularly continuous blood flow wearable and implantable devices. Here, highly controlled experiments to understand the effect of graphene oxide (GO) surface properties on its protein adsorption are presented. A newly developed self-assembly process is implemented to build a GO membrane with an atomically smooth surface to eliminate the effect of surface roughness on protein adsorption. The GO oxidation level is varied to change the overall membrane hydrophilicity while the nanoplatelets size and edge area is maintained constant. The fouling characteristics of the membrane are examined through scanning electron microscope imaging and long-term water flux measurements. These measurements unambiguously prove that proteins are primarily adsorbed on the basal areas of nanoplatelets, on the graphitic regions, away from the nanoplatelets edges. As a result, while decreasing the oxidation level reduced the overall surface hydrophilicity leading to more protein adsorption, the membrane mass flux is minimally impacted. Studies on a polymer membrane under similar conditions show expansion of protein agglomerates over time leading to formation of large biofilm domains, while the GO nanoplatelets edges function as a barrier to formation of an expansive biofilm.
引用
收藏
页数:6
相关论文
共 50 条
  • [41] Graphene oxide films, fibers, and membranes
    Cruz-Silva, Rodolfo
    Endo, Morinobu
    Terrones, Mauricio
    NANOTECHNOLOGY REVIEWS, 2016, 5 (04) : 377 - 391
  • [42] Graphene oxide membranes in fluid separations
    Chong, J. Y.
    Wang, B.
    Li, K.
    CURRENT OPINION IN CHEMICAL ENGINEERING, 2016, 12 : 98 - 105
  • [43] Biorefinery Separations with Graphene Oxide Membranes
    Nair, Sankar
    Chemical Engineering Progress, 2022, 118 (04) : 39 - 43
  • [44] Bio-inspired Fabrication of Anti-fouling and Stability of Nanofiltration Membranes with a Poly(dopamine)/Graphene Oxide Interlayer
    Wang, Tao
    Wang, Jin
    Zhao, Zhenzhen
    Zheng, Xi
    Li, Jiding
    Liu, Helei
    Zhao, Zhiping
    INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2021, 60 (41) : 14868 - 14883
  • [45] Applications of graphene oxide blended poly(vinylidene fluoride) membranes for the treatment of organic matters and its membrane fouling investigation
    Ai, Jing
    Yang, Lian
    Liao, Guiying
    Xia, Hua
    Xiao, Feng
    APPLIED SURFACE SCIENCE, 2018, 455 : 502 - 512
  • [46] A Raman Spectroscopic Analysis of Polymer Membranes with Graphene Oxide and Reduced Graphene Oxide
    Kolodziej, Anna
    Dlugon, Elzbieta
    Swietek, Malgorzata
    Ziabka, Magdalena
    Dawiec, Emilia
    Gubernat, Maciej
    Michalec, Marek
    Weselucha-Birczynska, Aleksandra
    JOURNAL OF COMPOSITES SCIENCE, 2021, 5 (01):
  • [47] Ultrafiltration Membranes Functionalized with Copper Oxide and Zwitterions for Fouling Resistance
    Hackett, Cannon
    Abolhassani, Mojtaba
    Greenlee, Lauren F.
    Thompson, Audie K.
    MEMBRANES, 2022, 12 (05)
  • [48] Graphene oxide functionalized polyethersulfone membrane to reduce organic fouling
    Igbinigun, Efosa
    Fennell, Yaolin
    Malaisamy, Ramamoorthy
    Jones, Kimberly L.
    Morris, Vernon
    JOURNAL OF MEMBRANE SCIENCE, 2016, 514 : 518 - 526
  • [49] Influence of the characteristics of natural organic matter on the fouling of microfiltration membranes
    Fan, LH
    Harris, JL
    Roddick, FA
    Booker, NA
    WATER RESEARCH, 2001, 35 (18) : 4455 - 4463
  • [50] Effects of electroflocculation/oxidation pretreatment on the fouling characteristics of ultrafiltration membranes
    Li, Yinghua
    Wang, Yiyan
    Liao, Mengxi
    Su, Fei
    Zhang, Yue
    Peng, Linlin
    WATER SCIENCE AND TECHNOLOGY, 2022, 85 (04) : 1079 - 1089