Protein Fouling Characteristics of Graphene Oxide Membranes

被引:6
|
作者
Rode, Richard [1 ]
Schmid, Michael [1 ]
Moghaddam, Saeed [1 ]
机构
[1] Univ Florida, Dept Mech Engn, Gainesville, FL 32611 USA
来源
ADVANCED MATERIALS INTERFACES | 2022年 / 9卷 / 04期
基金
美国国家卫生研究院;
关键词
2D materials; dialyzer; graphene oxide; membranes; protein fouling; NANOFILTRATION MEMBRANE; COMPOSITE FILMS; ADSORPTION; ULTRAFILTRATION; SURFACE; FLUX; MICROFILTRATION; HYDROPHILICITY; PERFORMANCE; NANOSHEETS;
D O I
10.1002/admi.202101613
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Advancing the knowledge of surfaces and protein interactions is paramount to development of non-fouling membranes for many applications, particularly continuous blood flow wearable and implantable devices. Here, highly controlled experiments to understand the effect of graphene oxide (GO) surface properties on its protein adsorption are presented. A newly developed self-assembly process is implemented to build a GO membrane with an atomically smooth surface to eliminate the effect of surface roughness on protein adsorption. The GO oxidation level is varied to change the overall membrane hydrophilicity while the nanoplatelets size and edge area is maintained constant. The fouling characteristics of the membrane are examined through scanning electron microscope imaging and long-term water flux measurements. These measurements unambiguously prove that proteins are primarily adsorbed on the basal areas of nanoplatelets, on the graphitic regions, away from the nanoplatelets edges. As a result, while decreasing the oxidation level reduced the overall surface hydrophilicity leading to more protein adsorption, the membrane mass flux is minimally impacted. Studies on a polymer membrane under similar conditions show expansion of protein agglomerates over time leading to formation of large biofilm domains, while the GO nanoplatelets edges function as a barrier to formation of an expansive biofilm.
引用
收藏
页数:6
相关论文
共 50 条
  • [1] Organic Fouling of Graphene Oxide Membranes and Its Implications for Membrane Fouling Control in Engineered Osmosis
    Hu, Meng
    Zheng, Sunxiang
    Mi, Baoxia
    ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2016, 50 (02) : 685 - 693
  • [2] Accessing of graphene oxide (GO) nanofiltration membranes for microbial and fouling resistance
    Wang, Jian
    Gao, Xueli
    Yu, Hui
    Wang, Qun
    Ma, Zhun
    Li, Zhaokui
    Zhang, Yushan
    Gao, Congjie
    SEPARATION AND PURIFICATION TECHNOLOGY, 2019, 215 : 91 - 101
  • [3] Quaternized polysulfone and graphene oxide nanosheet derived low fouling novel positively charged hybrid ultrafiltration membranes for protein separation
    Kumar, Mahendra
    McGlade, Declan
    Ulbricht, Mathias
    Lawler, Jenny
    RSC ADVANCES, 2015, 5 (63): : 51208 - 51219
  • [4] CHARACTERISTICS OF POLYMERIC ULTRAFILTRATION MEMBRANES PRODUCED WITH THE USE OF GRAPHENE OXIDE
    Tomczak, Elwira
    Blus, Martyna
    ECOLOGICAL CHEMISTRY AND ENGINEERING S-CHEMIA I INZYNIERIA EKOLOGICZNA S, 2018, 25 (03): : 419 - 429
  • [5] Low-Fouling Antibacterial Reverse Osmosis Membranes via Surface Grafting of Graphene Oxide
    Huang, Xinwei
    Marsh, Kristofer L.
    McVerry, Brian T.
    Hoek, Eric M. V.
    Kaner, Richard B.
    ACS APPLIED MATERIALS & INTERFACES, 2016, 8 (23) : 14334 - 14338
  • [6] Polyamide reverse osmosis membranes modified with graphene oxide for enhanced chlorine attack and fouling resistance
    Assis, Ana Luiza S.
    de Castro, Vinicius G.
    Brasil, Yara L.
    de Vasconcelos, Claudia K. B.
    Viana, Marcelo M.
    de Oliveira, Caique P. M.
    Silva, Glaura G.
    Brondi, Mariana G.
    Amaral, Miriam Cristina S.
    Nunes, Eduardo H. M.
    ENVIRONMENTAL SCIENCE-WATER RESEARCH & TECHNOLOGY, 2025, 11 (02) : 405 - 421
  • [7] Evaluation of Humic Acid and Tannic Acid Fouling in Graphene Oxide-Coated Ultrafiltration Membranes
    Chu, Kyoung Hoon
    Huang, Yi
    Yu, Miao
    Her, Namguk
    Flora, Joseph R. V.
    Park, Chang Min
    Kim, Suhan
    Cho, Jaeweon
    Yoon, Yeomin
    ACS APPLIED MATERIALS & INTERFACES, 2016, 8 (34) : 22270 - 22279
  • [8] Graphene Oxide Modified Polyamide 66 Ultrafiltration Membranes with Enhanced Anti-Fouling Performance
    Yan, Jiangyi
    Nie, Lihong
    Li, Guiliang
    Zhu, Yuanlu
    Gao, Ming
    Wu, Ruili
    Wang, Beifu
    MEMBRANES, 2022, 12 (05)
  • [9] Synergetic effects of oxidized carbon nanotubes and graphene oxide on fouling control and anti-fouling mechanism of polyvinylidene fluoride ultrafiltration membranes
    Zhang, Jiguo
    Xu, Zhiwei
    Shan, Mingjing
    Zhou, Baoming
    Li, Yinglin
    Li, Baodong
    Niu, Jiarong
    Qian, Xiaoming
    JOURNAL OF MEMBRANE SCIENCE, 2013, 448 : 81 - 92
  • [10] High flux and fouling resistant flat sheet polyethersulfone membranes incorporated with graphene oxide for ultrafiltration applications
    Abdel-Karim, Ahmed
    Leaper, Sebastian
    Alberto, Monica
    Vijayaraghavan, Aravind
    Fan, Xiaolei
    Holmes, Stuart M.
    Souaya, Eglal R.
    Badawy, Mohamed I.
    Gorgojo, Patricia
    CHEMICAL ENGINEERING JOURNAL, 2018, 334 : 789 - 799