Fetomaternal Hemorrhage: Can We Use Hemoglobin Electrophoresis as a Diagnostic Tool?

被引：11

作者：

Stanic, Zana ^{[1
]}

Stanisic, Lada ^{[2
]}

Fures, Rajko ^{[3
]}

Persec, Zoran ^{[4
]}

Dapic, Kresimir ^{[4
]}

Hrgovic, Zlatko ^{[5
]}

机构：

[1] Univ Hosp Ctr Split Krizine, Obstet & Gynecol Clin, Split, Croatia

[2] Univ Hosp Ctr Split Krizine, Dept Med Lab Diag, Split, Croatia

[3] Zabok Gen Hosp, Dept Gynecol & Obstet, Zabok, Croatia

[4] Univ Hosp Dubrava, Urol Dept, Ave Gojka Suska 6, Zagreb 10000, Croatia

[5] Goethe Univ Frankfurt, Gynekol, Frankfurt, Germany

来源：

ZEITSCHRIFT FUR GEBURTSHILFE UND NEONATOLOGIE | 2020年 / 224卷 / 03期

关键词：

Fetomaternal hemorrhage; Hemoglobin capillary electrophoresis; Fetomaternal transfusion; FLOW-CYTOMETRY; CAPILLARY-ELECTROPHORESIS; QUANTIFICATION;

D O I：

10.1055/a-1041-3443

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Fetomaternal hemorrhage (FMH) is usually detected by either the Kleihauer-Betke (KB) test or by 2 cytometry, the latter of which represents the gold standard of FMH diagnosis today. But what do we do when neither method is available? We present two cases of suspected FMH due to their characteristic signs and symptoms that were ultimately confirmed by hemoglobin electrophoresis (HE).

引用

页码：150 / 152

页数：3

共 11 条

[1] FETOMATERNAL HEMORRHAGE AS A CAUSE OF FETAL MORBIDITY AND MORTALITY
FAY, RA
[J]. BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1983, 90 (05): : 443 - 446
[2] Flow cytometric assessment of feto-maternal hemorrhage; a comparison with Betke-Kleihauer
Fernandes, Bernard J.
von Dadelszen, Peter
Fazal, Inez
Bansil, Nikki
Ryan, Greg
[J]. PRENATAL DIAGNOSIS, 2007, 27 (07) : 641 - 643
[3] OCCULT FETOMATERNAL HEMORRHAGE AS A CAUSE OF FETAL MORTALITY AND MORBIDITY
FLIEGNER, JRH
FORTUNE, DW
BARRIE, JU
[J]. AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY, 1987, 27 (02) : 158 - 161
[4] Comparison of Sebia Capillarys Flex capillary electrophoresis with the BioRad Variant II high pressure liquid chromatography in the evaluation of hemoglobinopathies
Greene, Dina N.
Pyle, Amy L.
Chang, Judy S.
Hoke, Carolyn
Lorey, Thomas
[J]. CLINICA CHIMICA ACTA, 2012, 413 (15-16) : 1232 - 1238
[5] Detection of fetomaternal hemorrhage following chorionic villus sampling by Kleihauer Betke test and rise in maternal serum alpha feto protein
Katiyar, Richa
Kriplani, Alka
Agarwal, Nutan
Bhatla, Neerja
Kabra, Madhulika
[J]. PRENATAL DIAGNOSIS, 2007, 27 (02) : 139 - 142
[6] Quantification of feto-maternal haemorrhage (FMH) by flow cytometry: anti-fetal haemoglobin labelling potentially underestimates massive FMH in comparison to labelling with anti-D
Kennedy, GA
Shaw, R
Just, S
Bryson, G
Battistutta, F
Rowell, J
Williams, B
[J]. TRANSFUSION MEDICINE, 2003, 13 (01) : 25 - 33
[7] Detection of fetomaternal hemorrhage
Kim, Yeowon A.
Makar, Robert S.
[J]. AMERICAN JOURNAL OF HEMATOLOGY, 2012, 87 (04) : 417 - 423
[8] The presence of F cells with a fetal phenotype in adults with hemoglobinopathies limits the utility of flow cytometry for quantitation of fetomaternal hemorrhage
Othman, Jad
Orellana, Daniel
Chen, Lin Selina
Russell, Megan
Khoo, Teh-Liane
[J]. CYTOMETRY PART B-CLINICAL CYTOMETRY, 2018, 94 (04) : 695 - 698
[9] Quantification of fetomaternal hemorrhage: A comparative study of the manual and automated microscopic Kleihauer-Betke tests and flow cytometry in clinical samples
Pelikan, Denise M.
Scherjon, Sicco A.
Mesker, Wilma E.
de Groot-Swings, Godelieve M.
Brouwer-Mandema, Geeske G.
Tanke, Hans J.
Kanhai, Humphrey H.
[J]. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2004, 191 (02) : 551 - 557
[10] Capillary Electrophoresis-Mass Spectrometry for Clinical Metabolomics
Ramautar, Rawi
[J]. ADVANCES IN CLINICAL CHEMISTRY, VOL 74, 2016, 74 : 1 - 34

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