Telomeres and telomerases: intimations of immortality

被引：3

作者：

Crocker, J ^{[1
]}

机构：

[1] Birmingham Heartlands Hosp, Dept Cellular Pathol, Birmingham B9 5SS, W Midlands, England

来源：

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY | 2001年 / 13卷 / 08期

关键词：

cell senescence; telomerase; telomeres;

D O I：

10.1097/00042737-200108000-00002

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

There is a constant balance in cancer cells between division and death. The malignant phenotype is associated with a continuing cell cycle or 'immortalization'. Telomeres, structures that cap the chromosomes, are related to cell longevity and are regulated by a ribonucleoprotein called telomerase. This review describes the possible roles of telomeres and telomerase in the malignant process. Eur J Gastroenterol Hepatol 13:889-890 (C) 2001 Lippincott Williams & Wilkins.

引用

页码：889 / 890

页数：2

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