Ameliorative effects of paricalcitol against 1800-MHz mobile phone radiation-induced skin damage in rats

被引:0
作者
Aktas, Savas [1 ]
Comelekoglu, Ulku [2 ]
Demirbag, Burcu [3 ]
Kibar, Deniz [1 ]
Uzun, Cosar [2 ]
Yildirim, Metin [4 ]
Ozdemir, Erkin [2 ]
Engiz, Begum Korunur [5 ]
Sogut, Fatma [6 ]
Akar, Aysegul [7 ]
Yalin, Serap [4 ]
机构
[1] Mersin Univ, Fac Med, Dept Histol & Embryol, TR-33342 Mersin, Turkey
[2] Mersin Univ, Fac Med, Dept Biophys, Mersin, Turkey
[3] Mersin Univ, Adv Technol Educ Res & Applicat Ctr, Mersin, Turkey
[4] Mersin Univ, Fac Pharm, Dept Biochem, Mersin, Turkey
[5] Ondokuz Mayis Univ, Fac Engn, Dept Elect & Elect Engn, Samsun, Turkey
[6] Mersin Univ, Vocat Sch Med Serv, Dept Perfus Technol, Mersin, Turkey
[7] Ondokuz Mayis Univ, Fac Med, Dept Biophys, Samsun, Turkey
关键词
1800-MHz RF; paricalcitol; skin; oxidative stress; OXIDATIVE STRESS; GSM-1800; SIGNALS; HAIRLESS RATS; VITAMIN-D; GSM-900; MECHANISMS; PROTECTION; APOPTOSIS; RESPONSES; EXPOSURE;
D O I
10.1080/02772248.2020.1721500
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
This study aimed to evaluate the protective role of paricalcitol, a vitamin D analog, against hazardous effects of 1800MHz radiofrequency (RF) radiation on the skin of male Wistar albino rats exposed one h/day for 4weeks. The maximum specific absorption rate was calculated as 0.0042W/kg. Superoxide dismutase and catalase activity, collagen bundle thickness, breaking force, energy, and stress were decreased, while malondialdehyde level and mast cell number were increased. The exposure to 1800-MHz RF radiation caused a reduction in skin biomechanical quality through oxidative stress and mast cell activation. The administration of paricalcitol caused a significant improvement.
引用
收藏
页码:508 / 525
页数:18
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