Clozapine, HIV and neutropenia: a case report

被引：3
作者：
Whiskey, Eromona [1 ]
O'Flynn, David [2 ]
Taylor, David [1 ,3 ]
机构：
[1] Maudsley Hosp & Inst Psychiat, Pharm Dept, Denmark Hill, London SE5 8AZ, England
[2] South London & Maudsley NHS Fdn Trust, Dept Rehabil Psychiat, London, England
[3] Kings Coll London, Inst Pharmaceut Sci, London, England
来源：
THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY | 2018年 / 8卷 / 12期
关键词：
Clozapine; neutropenia; HIV; anti-retroviral agents; drug interactions; BENIGN ETHNIC NEUTROPENIA; AGRANULOCYTOSIS; PSYCHOSIS; SCHIZOPHRENIA; UK;
D O I：
10.1177/2045125318804499
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
There is paucity of information on the use of clozapine in patients with HIV. Ethnicity, co-prescribed medications and possible drug-drug interactions are important considerations in evaluating risk of blood dyscrasias during clozapine treatment. Individuals with HIV should not be denied access to the most effective antipsychotic, but a multidisciplinary approach is essential for optimal outcome in such complex patients.
引用
收藏
页码：365 / 369
页数：5
相关论文
共 20 条
  • [11] Lera G, 1999, MOVEMENT DISORD, V14, P128, DOI 10.1002/1531-8257(199901)14:1<128::AID-MDS1021>3.0.CO
  • [12] 2-J
  • [13] Levine AM, 2006, ARCH INTERN MED, V166, P405, DOI 10.1001/.405
  • [14] Sodium valproate and clozapine induced neutropenia: A case control study using register data
    Malik, Steffi
    Lally, John
    Ajnakina, Olesya
    Pritchard, Megan
    Krivoy, Amir
    Gaughran, Fiona
    Shetty, Hitesh
    Flanagan, Robert J.
    MacCabe, James H.
    [J]. SCHIZOPHRENIA RESEARCH, 2018, 195 : 267 - 273
  • [15] Cobicistat versus ritonavir boosting and differences in the drug-drug interaction profiles with co-medications
    Marzolini, Catia
    Gibbons, Sara
    Khoo, Saye
    Back, David
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2016, 71 (07) : 1755 - 1758
  • [16] Active monitoring of 12760 clozapine recipients in the UK and Ireland - Beyond pharmacovigilance
    Munro, J
    O'Sullivan, D
    Andrews, C
    Arana, A
    Mortimer, A
    Kerwin, R
    [J]. BRITISH JOURNAL OF PSYCHIATRY, 1999, 175 : 576 - 580
  • [17] Clozapine Use in HIV-Infected Schizophrenia Patients: A Case-Based Discussion and Review
    Nejad, Shamim Hashemi
    Gandhi, Rajesh T.
    Freudenreich, Oliver
    [J]. PSYCHOSOMATICS, 2009, 50 (06) : 626 - 632
  • [18] Schizophrenia and HIV
    Sewell, DD
    [J]. SCHIZOPHRENIA BULLETIN, 1996, 22 (03) : 465 - 473
  • [19] Haematological manifestations of human immune deficiency virus infection
    Vishnu, Prakash
    Aboulafia, David M.
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 2015, 171 (05) : 695 - 709
  • [20] The importance of the recognition of benign ethnic neutropenia in black patients during treatment with clozapine: case reports and database study
    Whiskey, Eromona
    Olofinjana, Olubanke
    Taylor, David
    [J]. JOURNAL OF PSYCHOPHARMACOLOGY, 2011, 25 (06) : 842 - 845
12