Clozapine, HIV and neutropenia: a case report

被引：3
作者：
Whiskey, Eromona [1 ]
O'Flynn, David [2 ]
Taylor, David [1 ,3 ]
机构：
[1] Maudsley Hosp & Inst Psychiat, Pharm Dept, Denmark Hill, London SE5 8AZ, England
[2] South London & Maudsley NHS Fdn Trust, Dept Rehabil Psychiat, London, England
[3] Kings Coll London, Inst Pharmaceut Sci, London, England
来源：
THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY | 2018年 / 8卷 / 12期
关键词：
Clozapine; neutropenia; HIV; anti-retroviral agents; drug interactions; BENIGN ETHNIC NEUTROPENIA; AGRANULOCYTOSIS; PSYCHOSIS; SCHIZOPHRENIA; UK;
D O I：
10.1177/2045125318804499
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
There is paucity of information on the use of clozapine in patients with HIV. Ethnicity, co-prescribed medications and possible drug-drug interactions are important considerations in evaluating risk of blood dyscrasias during clozapine treatment. Individuals with HIV should not be denied access to the most effective antipsychotic, but a multidisciplinary approach is essential for optimal outcome in such complex patients.
引用
收藏
页码：365 / 369
页数：5
相关论文
共 20 条
  • [1] CLOZAPINE-INDUCED AGRANULOCYTOSIS - INCIDENCE AND RISK-FACTORS IN THE UNITED-STATES
    ALVIR, JMJ
    LIEBERMAN, JA
    SAFFERMAN, AZ
    SCHWIMMER, JL
    SCHAAF, JA
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1993, 329 (03) : 162 - 167
  • [2] [Anonymous], 2015, MAUDSLEY PRESCRIBING
  • [3] Neutropenia and agranulocytosis in patients receiving clozapine in the UK and Ireland
    Atkin, K
    Kendall, F
    Gould, D
    Freeman, H
    Lieberman, J
    OSullivan, D
    [J]. BRITISH JOURNAL OF PSYCHIATRY, 1996, 169 (04) : 483 - 488
  • [4] Use of antipsychotic medications among HIV-infected individuals with schizophrenia
    Bagchi, A
    Sambamoorthi, U
    McSpiritt, E
    Yanos, P
    Walkup, J
    Crystal, S
    [J]. SCHIZOPHRENIA RESEARCH, 2004, 71 (2-3) : 435 - 444
  • [5] Co-occurrence of HIV and serious mental illness among Medicaid recipients
    Blank, MB
    Mandell, DS
    Aiken, L
    Hadley, TR
    [J]. PSYCHIATRIC SERVICES, 2002, 53 (07) : 868 - 873
  • [6] Clozapine treatment of HIV-associated psychosis - too much bone marrow toxicity?
    Dettling, M
    Muller-Oerlinghausen, B
    Britsch, P
    [J]. PHARMACOPSYCHIATRY, 1998, 31 (04) : 156 - 157
  • [7] Dolder CR, 2004, AIDS, V18, pS35, DOI 10.1097/00002030-200401001-00006
  • [8] The concomitant use of second-generation antipsychotics and long-term antiretroviral therapy may be associated with increased cardiovascular risk
    Ferrara, Maria
    Umlauf, Anya
    Sanders, Chelsea
    Meyer, Jonathan M.
    McCutchan, John Allen
    Duarte, Nichole
    Atkinson, Joseph Hampton
    Grant, Igor
    Ellis, Ronald J.
    [J]. PSYCHIATRY RESEARCH, 2014, 218 (1-2) : 201 - 208
  • [9] Benign ethnic neutropenia: What is a normal absolute neutrophil count?
    Haddy, TB
    Rana, SR
    Castro, O
    [J]. JOURNAL OF LABORATORY AND CLINICAL MEDICINE, 1999, 133 (01): : 15 - 22
  • [10] Clozapine-Associated Agranulocytosis Treatment With Granulocyte Colony-Stimulating Factor/Granulocyte-Macrophage Colony-Stimulating Factor: A Systematic Review
    Lally, John
    Malik, Steffi
    Whiskey, Eromona
    Taylor, David M.
    Gaughran, Fiona P.
    Krivoy, Amir
    Flanagan, Robert J.
    Mijovic, Aleksandar
    MacCabe, James H.
    [J]. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 2017, 37 (04) : 441 - 446
12