Clozapine, HIV and neutropenia: a case report

被引:4
作者
Whiskey, Eromona [1 ]
O'Flynn, David [2 ]
Taylor, David [1 ,3 ]
机构
[1] Maudsley Hosp & Inst Psychiat, Pharm Dept, Denmark Hill, London SE5 8AZ, England
[2] South London & Maudsley NHS Fdn Trust, Dept Rehabil Psychiat, London, England
[3] Kings Coll London, Inst Pharmaceut Sci, London, England
关键词
Clozapine; neutropenia; HIV; anti-retroviral agents; drug interactions; BENIGN ETHNIC NEUTROPENIA; AGRANULOCYTOSIS; PSYCHOSIS; SCHIZOPHRENIA; UK;
D O I
10.1177/2045125318804499
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
There is paucity of information on the use of clozapine in patients with HIV. Ethnicity, co-prescribed medications and possible drug-drug interactions are important considerations in evaluating risk of blood dyscrasias during clozapine treatment. Individuals with HIV should not be denied access to the most effective antipsychotic, but a multidisciplinary approach is essential for optimal outcome in such complex patients.
引用
收藏
页码:365 / 369
页数:5
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