Superselective Conventional Transarterial Chemoembolization for Hepatocellular Carcinoma: Rationale, Technique, and Outcome

被引:57
作者
Miyayama, Shiro [1 ]
Matsui, Osamu [2 ]
机构
[1] Fukuiken Saiseikai Hosp, Dept Diagnost Radiol, 7-1 Funabashi,Wadanaka Cho, Fukui 9188503, Japan
[2] Kanazawa Univ, Grad Sch Med Sci, Dept Radiol, Takara Machi, Kanazawa, Ishikawa, Japan
关键词
TRANSCATHETER ARTERIAL CHEMOEMBOLIZATION; IODIZED OIL; HEPATIC-ARTERY; PORTAL-VEIN; TUMOR; EMBOLIZATION; LIVER; THERAPY; CT; SURVIVAL;
D O I
10.1016/j.jvir.2016.04.014
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Conventional transarterial chemoembolization with ethiodized oil and gelatin sponge (GS) particles is a standard technique for hepatocellular carcinoma: Ethiodized oilcan temporarily block tumor sinusoids, portal venules, hepatic sinusoids, and arterial microconimunications. By adding GS embolization, strong ischemic effects not only on the tumor but also on the surrounding liver parenchyma can be achieved. Superselective conventional transarterial chemoembolization is mainly indicated for patients with Child-Pugh scores of 5-8, tumors <= 7 cm, and <= 5 lesions. According to a Japanese nationwide survey, the 5-year survival rate of patients with Child-Pugh class A and a single tumor was 52%.
引用
收藏
页码:1269 / 1278
页数:10
相关论文
共 68 条
[51]   Intrahepatic recurrences of hepatocellular carcinoma after hepatectomy - Analysis based on tumor hemodynamics [J].
Sakon, M ;
Nagano, H ;
Nakamori, S ;
Dono, K ;
Umeshita, K ;
Murakami, T ;
Nakamura, H ;
Monden, M .
ARCHIVES OF SURGERY, 2002, 137 (01) :94-99
[52]   Microsatellite distribution and indication for locoregional therapy in small hepatocellular carcinoma [J].
Sasaki, A ;
Kai, S ;
Iwashita, Y ;
Hirano, S ;
Ohta, M ;
Kitano, S .
CANCER, 2005, 103 (02) :299-306
[53]   Which Response Criteria Best Help Predict Survival of Patients with Hepatocellular Carcinoma Following Chemoembolization? A Validation Study of Old and New Models [J].
Shim, Ju Hyun ;
Lee, Han Chu ;
Kim, Seon-Ok ;
Shin, Yong Moon ;
Kim, Kang Mo ;
Lim, Young-Suk ;
Suh, Dong Jin .
RADIOLOGY, 2012, 262 (02) :708-718
[54]   Transarterial Chemoembolization for Hepatocellular Carcinoma with a New Generation of Beads: Clinical-Radiological Outcomes and Safety Profile [J].
Spreafico, Carlo ;
Cascella, Tommaso ;
Facciorusso, Antonio ;
Sposito, Carlo ;
Rodolfo, Lanocita ;
Morosi, Carlo ;
Civelli, Enrico M. ;
Vaiani, Marta ;
Bhoori, Sherrie ;
Pellegrinelli, Alessandro ;
Marchiano, Alfonso ;
Mazzaferro, Vincenzo .
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 2015, 38 (01) :129-134
[55]   RESPONSE OF EARLY-STAGE HEPATOCELLULAR-CARCINOMA AND BORDERLINE LESIONS TO THERAPEUTIC ARTERIAL EMBOLIZATION [J].
TAKAYASU, K ;
WAKAO, F ;
MORIYAMA, N ;
MURAMATSU, Y ;
SAKAMOTO, M ;
HIROHASHI, S ;
MAKUUCHI, M ;
KOSUGE, T ;
TAKAYAMA, T ;
YAMAZAKI, S .
AMERICAN JOURNAL OF ROENTGENOLOGY, 1993, 160 (02) :301-306
[56]   Targeted transarterial oily chemoembolization for small foci of hepatocellular carcinoma using a unified helical CT and angiography system: Analysis of factors affecting local recurrence and survival rates [J].
Takayasu, K ;
Muramatsu, Y ;
Maeda, T ;
Iwata, R ;
Furukawa, H ;
Muramatsu, Y ;
Moriyama, N ;
Okusaka, T ;
Okada, S ;
Ueno, H .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2001, 176 (03) :681-688
[57]   Prospective cohort study of transarterial chemoembolization for unresectable hepatocellular carcinoma in 8510 patients [J].
Takayasu, Kenichi ;
Arii, Shigeki ;
Ikai, Iwao ;
Omata, Masao ;
Okita, Kiwamu ;
Ichida, Takafumi ;
Matsuyama, Yutaka ;
Nakanuma, Yasuni ;
Kojiro, Masamichi ;
Makuuchi, Masatoshi ;
Yamaoka, Yoshio .
GASTROENTEROLOGY, 2006, 131 (02) :461-469
[58]   Superselective transarterial chemoembolization for hepatocellular carcinoma. Validation of treatment algorithm proposed by Japanese guidelines [J].
Takayasu, Kenichi ;
Arii, Shigeki ;
Kudo, Masatoshi ;
Ichida, Takafumi ;
Matsui, Osamu ;
Izumi, Namiki ;
Matsuyama, Yutaka ;
Sakamoto, Michiie ;
Nakashima, Osamu ;
Ku, Yonson ;
Kokudo, Norihiro ;
Makuuchi, Masatoshi .
JOURNAL OF HEPATOLOGY, 2012, 56 (04) :886-892
[59]   Overall Survival After Transarterial Lipiodol Infusion Chemotherapy With or Without Embolization for Unresectable Hepatocellular Carcinoma: Propensity Score Analysis [J].
Takayasu, Kenichi ;
Arii, Shigeki ;
Ikai, Iwao ;
Kudo, Masatoshi ;
Matsuyama, Yutaka ;
Kojiro, Masamichi ;
Makuuchi, Masatoshi .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2010, 194 (03) :830-837
[60]   Accumulation of iodized oil within the non-neoplastic liver adjacent to hepatocellular carcinoma via the drainage routes of the tumor after transcatheter arterial embolization [J].
Terayama, N ;
Matsui, O ;
Gabata, T ;
Kobayashi, S ;
Sanada, J ;
Ueda, K ;
Kadoya, M ;
Kawamori, Y .
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 2001, 24 (06) :383-387