The lung and gut microbiome: what has to be taken into consideration for cystic fibrosis?

被引:28
作者
Hery-Arnaud, Genevieve [1 ,2 ]
Boutin, Sebastien [3 ,4 ]
Cuthbertson, Leah [5 ]
Elborn, Stuart J. [5 ,6 ]
Tunney, Michael M. [7 ]
机构
[1] Univ Brest, EFS, GGB, INSERM,UMR 1078, F-29200 Brest, France
[2] CHRU Brest, Hop La Cavale Blanche, Unite Bacteriol, Pole Biol Pathol, Brest, France
[3] Heidelberg Univ Hosp, Dept Infect Dis Med Microbiol & Hyg, Heidelberg, Germany
[4] German Ctr Lung Res DZL, Translat Lung Res Ctr Heidelberg TLRC, Heidelberg, Germany
[5] Imperial Coll, Natl Heart & Lung Inst, London, England
[6] Queens Univ Belfast, Sch Med Dent & Biomed Sci, Ctr Expt Med, Halo Res Grp, Belfast, Antrim, North Ireland
[7] Queens Univ Belfast, Sch Pharm, Halo Res Grp, Belfast, Antrim, North Ireland
关键词
Microbiome; Cystic Fibrosis; Lung; Gut; Dysbiosis; ANAEROBIC-BACTERIA; RESISTANCE; AGE; PH;
D O I
10.1016/j.jcf.2018.11.003
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
The 15th European Cystic Fibrosis Society (ECFS) Basic Science pre-conference Symposium focused on the topic of the microbiome, asking the question "The lung and gut microbiome: what has to be considered for cystic fibrosis (CF)?" This review gives an overview of the main points raised during the symposium, which dealt with the technical considerations, pathophysiology and clinical implications of the microbiome in CF. (C) 2018 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:13 / 21
页数:9
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